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Table 1 Analysis of the PTPN22 C1858T variant in the Spanish cohort

From: Susceptibility to type 1 diabetes conferred by the PTPN22C1858T polymorphism in the Spanish population

  Genotypes (%) Alleles (%)
Subjects CC CT TT C T
Controls (n = 554) 483 (87.2) 68 (12.3) 3 (0.5) 1034 (93.3) 74 (6.7)
   Female (n = 197) 172 (87.3) 23 (11.7) 2 (1.0) 367 (93.1) 27 (6.9)
   Male (n = 189) 168 (89.9) 20 (10.6) 1 (0.5) 356 (94.2) 22 (5.8)
Cases (n = 316) 252 (79.7) 59 (18.7) 5 (1.6) 563 (89.1) 69 (10.9)
   Female (n = 159) 122 (76.7) 33 (20.8) 4 (2.5) 277 (87.1) 41 (12.9)
   Male (n = 157) 130 (82.8) 26 (16.1) 1 (0.6) 286 (91.1) 28 (8.9)
  1. Patients vs. controls:
  2. T vs. C; OR (95%) = 1.71 (1.20–2.45); p = 0.002
  3. (TT+CT) vs. CC; OR (95%) = 1.73 (1.17–2.54); p = 0.004