Resequencing PNMTin European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1

Table 2 Allele (major) and genotype (major homozygote, heterozygote) frequencies for identified SNPs by resequencing in Estonian and Czech normotensives and hypertensives

SNP^a	dbSNP	Allele^b/Genotype	Estonians		Czech
			Normotensives	Hypertensives	Normotensives	Hypertensives
SNP-702	NA	G	1	1	0.96	0.98
5'UTR		GG	1	1	0.92	0.96
		GA	0	0	0.08	0.04
SNP-591	NA	G	0.96	0.96	0.98	0.88
5'UTR		GG	0.92	0.92	0.96	0.88
		GT	0.08	0.08	0.04	0
SNP-390	NA	A	0.60	0.70	0.85	0.675
5'UTR		AA	0.44	0.40	0.79	0.45
		AG	0.32	0.60	0.125	0.45
SNP-184	rs876493	A	0.60	0.58	0.66	0.54
5'UTR		AA	0.40	0.24	0.44	0.20
		GA	0.40	0.68	0.44	0.68
SNP+360	rs200173	G	0.98	1	0.96	0.96
Intron 1		GG	0.96	1	0.92	0.92
		AG	0.04	0	0.08	0.08
SNP+1520	rs5638	A	0.94	0.96	0.94	0.96
Exon 3		AA	0.92	0.92	0.88	0.92
		AG	0.04	0.08	0.12	0.08
SNP+1587	NA	G	0.98	1	1	0.98
Exon 3		GG	0.96	1	1	0.96
		AG	0.04	0	0	0.04

ISSN: 1471-2350