Skip to main content

Table 1 Significant association of MH30, CT60 and JO31 to autoimmune disease in northern Sweden.

From: CT60 genotype does not affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden

MH30

Case (%)

Control (%)

OR (95%CI)

P value

CC

16 (6.7)

108 (13.9)

  

CG

111 (46.4)

362 (46.6)

  

GG

112 (46.9)

307 (39.5)

  

CG vs. CC

  

2.07 (1.18–3.65)

0.01

GG vs. CC

  

2.46 (1.40–4.35)

0.002

Multiplicative model

  

1.40 (1.12–1.75)

0.004

Success rate (%)

94.5

89.9

  

CT60

    

AA

15 (6.4)

117 (14.4)

  

AG

111 (47.2)

394 (48.5)

  

GG

109 (46.4)

301 (37.1)

  

AG vs. AA

  

2.20 (1.23–3.91)

0.008

GG vs. AA

  

2.83 (1.58–5.05)

5 × 10-4

Multiplicative model

  

1.50 (1.19–188)

5 × 10-4

Success rate (%)

92.9

93.9

  

JO31

    

TT

18 (7.4)

131 (15.2)

  

GT

116 (47.7)

414 (48.1)

  

GG

109 (44.9)

316 (36.7)

  

GT vs. TT

  

2.04 (1.20–3.48)

0.009

GG vs. TT

  

2.51 (1.47–4.30)

8 × 10-4

Multiplicative model

  

1.44 (1.15–1.79)

0.001

Success rate (%)

96.0

99.5

  
  1. Allelic discrimination was used to genotype MH30 (rs231806), CT60 (rs30807243) and JO31 (rs11571302) in 253 cases and 865 controls from northern Sweden.