Skip to main content

Advertisement

Table 1 Significant association of MH30, CT60 and JO31 to autoimmune disease in northern Sweden.

From: CT60 genotype does not affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden

MH30 Case (%) Control (%) OR (95%CI) P value
CC 16 (6.7) 108 (13.9)   
CG 111 (46.4) 362 (46.6)   
GG 112 (46.9) 307 (39.5)   
CG vs. CC    2.07 (1.18–3.65) 0.01
GG vs. CC    2.46 (1.40–4.35) 0.002
Multiplicative model    1.40 (1.12–1.75) 0.004
Success rate (%) 94.5 89.9   
CT60     
AA 15 (6.4) 117 (14.4)   
AG 111 (47.2) 394 (48.5)   
GG 109 (46.4) 301 (37.1)   
AG vs. AA    2.20 (1.23–3.91) 0.008
GG vs. AA    2.83 (1.58–5.05) 5 × 10-4
Multiplicative model    1.50 (1.19–188) 5 × 10-4
Success rate (%) 92.9 93.9   
JO31     
TT 18 (7.4) 131 (15.2)   
GT 116 (47.7) 414 (48.1)   
GG 109 (44.9) 316 (36.7)   
GT vs. TT    2.04 (1.20–3.48) 0.009
GG vs. TT    2.51 (1.47–4.30) 8 × 10-4
Multiplicative model    1.44 (1.15–1.79) 0.001
Success rate (%) 96.0 99.5   
  1. Allelic discrimination was used to genotype MH30 (rs231806), CT60 (rs30807243) and JO31 (rs11571302) in 253 cases and 865 controls from northern Sweden.