Table 2 Allele and genotype frequencies (F) of SNPs and their association status with chronic renal insufficiency

TGFβ1

G>A (-800)

G = 0.93 (418)

A = 0.07 (32)

G = 0.91 (356)

A = 0.09 (72)

GG = 0.87 (196)

GA = 0.12 (27)

AA = 0.01 (3)

GG = 0.84(165)

GA = 0.15 (29)

AA = 0.01 (2)

χ² = 0.60;

P = 0.44

χ² = 1.16;

P = 0.56

TGFβ1

C>T (-509)

C = 0.875 (388)

T = 0.125 (112)

C = 0.84 (330)

T = 0.16 (124)

CC = 0.77 (171)

CT = 0.21 (47)

TT = 0.02 (4)

CC = 0.72 (141)

CT = 0.24 (47)

TT = 0.04 (8)

χ² = 1.24;

P = 0.27

χ² = 1.23;

P = 0.54

TNFα

G>A (-308)

Promoter

G = 0.93 (416)

A = 0.07 (32)

G = 0.96 (376)

A = 0.04 (16)

GG = 0.87 (195)

GA = 0.12 (27)

AA = 0.01 (2)

GG = 0.91 (178)

GA = 0.08 (16)

AA = 0.01 (2)

χ² = 2.31;

P = 0.13

χ² = 2.43;

P = 0.12

CCR2

C>T

Val64Ile

C = 0.91 (410)

T = 0.09 (40)

C = 0.94 (368)

T = 0.06 (24)

CC = 0.84 (189)

CT = 0.15 (34)

TT = 0.01 (2)

CC = 0.90 (176)

CT = 0.09 (18)

TT = 0.01 (2)

χ² = 2.73;

P = 0.10

χ² = 2.87;

P = 0.24

CCR

5G>A (59029)

G = 0.46 (208)

A = 0.54 (242)

G = 0.38 (148)

A = 0.62 (244)

GG = 0.21 (47)

GA = 0.49 (111)

AA = 0.30 (67)

GG = 0.14 (27)

GA = 0.48 (94)

AA = 0.38 (75)

χ² = 5.13;

P = 0.02

χ² = 5.22;

P = 0.07