Table 2 Plasma lipid levels according to PCSK9 E670G genotype
MEN | WOMEN | ||||
|---|---|---|---|---|---|
EE | EG | GG | EE | EG | |
A. All patients | |||||
n | 213 | 23 | 3 | 245 | 22 |
Total cholesterol (mg/dl) | 251 (74) | 251 (58) | 279 (56) | 287 (81) | 285 (83) |
LDL (mg/dl) | 183 (74) | 176 (51) | 210 (70) | 204 (79) | 206 (86) |
HDL (mg/dl) | 44 (12) | 47 (11) | 41 (15) | 60 (17) | 59 (19) |
Triglycerides (mg/dl) | 122 (12) | 136 (40) | 142 (40) | 117 (40) | 108 (36) |
Lipoprotein (a) (mg/dl) | 22 (30) | 20 (22) | 18 (12) | 29 (35) | 27 (33) |
B. Monogenic Hypercholesterolemia excluded | |||||
n | 190 | 23 | 3 | 210 | 18 |
Total cholesterol (mg/dl) | 234 (54) | 251 (58) | 279 (56) | 264 (56) | 257 (57) |
LDL (mg/dl) | 166 (52) | 176 (51) | 210 (70) | 180 (56) | 174 (53) |
HDL (mg/dl) | 45 (12) | 47 (11) | 41 (15) | 60 (17) | 61 (20) |
Triglycerides (mg/dl) | 123 (40) | 136 (40) | 142 (40) | 117 (40) | 108 (20) |
Lipoprotein (a) (mg/dl) | 21 (30) | 20 (22) | 18 (12) | 29 (34) | 29 (23) |