Figure 1

Frequency of the G allele of the 23968A>G (E670G) SNP in the PCSK9 gene according to LDL levels. Probands were grouped into below the 50^th percentile of LDL for age and sex, 50^th–95^th percentile and above the 95^th percentile. In Pol Hchol are included probands with LDL above the 95^th percentile for age and sex but had neither LDL above 300 mg/dl nor were heterozygous for the R3500Q mutation in the APOB gene. The number of patients in each group is indicated.