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Table 2 Genes with higher expression in mutant samples on microarray analysis. This table contains a list of genes with higher expression in mutant T-lymphocyte clones by one-way ANOVA analysis (p < 0.05). * indicates >1.5-fold change in expression level and ** indicates >2-fold change in expression level.

From: Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients

No. Gene Name P-value Common name Genbank No. Description
1 219759_at 6.66E-11 LRAP NM_022350 leukocyte-derived arginine aminopeptidase
2 206148_at 0.000152 IL3RA NM_002183 interleukin 3 receptor, alpha (low affinity)
3* 213655_at 0.000209 YWHAE AA502643 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
4* 212952_at 0.000278 MNT AA910371 calreticulin
5 218340_s_at 0.000346 FLJ10808 NM_018227 hypothetical protein FLJ10808
6* 200765_x_at 0.000507 CTNNA1 NM_001903 catenin (cadherin-associated protein), alpha 1, 102 kDa
7* 210732_s_at 0.000704 LGALS8 AF342816 lectin, galactoside-binding, soluble, 8 (galectin 8)
8 219974_x_at 0.00131 ECHDC1 NM_018479 enoyl Coenzyme A hydratase domain containing 1
9 202732_at 0.00142 PKIG NM_007066 protein kinase (cAMP-dependent, catalytic) inhibitor γ
10 204418_x_at 0.00183 GSTM4 NM_000848 glutathione S-transferase M2 (muscle)
11 221754_s_at 0.00187 CORO1B AI341234 coronin, actin binding protein, 1B
12* 219648_at 0.00266 FLJ10116 NM_018000 hypothetical protein FLJ10116
13* 212099_at 0.00528 RHOB AI263909 ras homolog gene family, member B
14 213135_at 0.00579 TIAM1 U90902 T-cell lymphoma invasion and metastasis 1
15** 210844_x_at 0.00603 CTNNA1 D14705 catenin (cadherin-associated protein), alpha 1, 102 kDa
16 208743_s_at 0.00617 YWHAB BC001359 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
17* 204201_s_at 0.00621 PTPN13 NM_006264 protein tyrosine phosphatase, non-receptor type 13
18* 222146_s_at 0.00628 TCF4 AK026674 transcription factor 4
19* 214130_s_at 0.00717 PDE4DIP AI821791 phosphodiesterase 4D interacting protein (myomegalin)
20** 211893_x_at 0.00833 CD6 U66145 CD6 antigen
21** 210136_at 0.00975 MBP AW070431 myelin basic protein
22** 209012_at 0.0106 TRIO AV718192 triple functional domain (PTPRF interacting)
23 222173_s_at 0.0109 TBC1D2 AK026105 TBC1 domain family, member 2
24 218435_at 0.0112 DNAJD1 NM_013238 DnaJ (Hsp40) homolog, subfamily D, member 1
25 210354_at 0.0122 IFNG M29383 Human mRNA for HuIFN-gamma interferon.
26 217744_s_at 0.0132 PERP NM_022121 PERP, TP53 apoptosis effector
27* 213822_s_at 0.0133 UBE3B BE856776 ubiquitin protein ligase E3B
28 204412_s_at 0.015 NEFH NM_021076 neurofilament, heavy polypeptide 200 kDa
29 200862_at 0.0151 DHCR24 NM_014762 24-dehydrocholesterol reductase
30 210949_s_at 0.0153 EIF3S8 BC000533 eukaryotic translation initiation factor 3, subunit 8, 110 kDa
31 218393_s_at 0.0172 SMU1 NM_018225 homolog of C. elegans smu-1
32 221550_at 0.018 COX15 BC002382 COX15 homolog, cytochrome c oxidase assembly protein
33* 203413_at 0.0192 NELL2 NM_006159 NEL-like 2 (chicken)
34 221036_s_at 0.0192 PSFL NM_031301 anterior pharynx defective 1B-like
35* 210915_x_at 0.0208 PRSS1 M15564 T-cell receptor precursor
36 218943_s_at 0.0212 DDX58 NM_014314 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
37 207813_s_at 0.0215 FDXR NM_004110 ferredoxin reductase
38 221021_s_at 0.0216 CTNNBL1 NM_030877 catenin, beta like 1
39 214316_x_at 0.0216 MNT AI378706 Calreticulin
40** 209728_at 0.022 HLA-DRB4 BC005312 major histocompatibility complex, class II, DR beta 3
41 215230_x_at 0.0229 EIF3S8 AA679705 eukaryotic translation initiation factor 3, subunit 8, 110 kDa
42 219269_at 0.024 FLJ21616 NM_024567 hypothetical protein FLJ21616
43** 207533_at 0.0246 CCL1 NM_002981 chemokine (C-C motif) ligand 1
44 207275_s_at 0.0255 ACSL1 NM_001995 acyl-CoA synthetase long-chain family member 1
45 217856_at 0.0274 RBM8A AF182415 RNA binding motif protein 8A
46 200647_x_at 0.0277 EIF3S8 NM_003752 eukaryotic translation initiation factor 3, subunit 8, 110 kDa
47* 214395_x_at 0.028 PP3856 AI335509 eukaryotic translation elongation factor 1 delta
48** 211900_x_at 0.0297 CD6 U66146 CD6 antigen
49 215606_s_at 0.0307 ELKS AB029004 Rab6-interacting protein 2
50 218945_at 0.0311 MGC2654 NM_024109 hypothetical protein MGC2654
51 209790_s_at 0.0314 CASP6 BC000305 caspase 6, apoptosis-related cysteine protease
52 201143_s_at 0.0325 EIF2S1 BC002513 eukaryotic translation initiation factor 2, subunit 1 alpha, 35 kDa
53 211965_at 0.0332 ZFP36L1 BE620915 zinc finger protein 36, C3H type-like 1
54** 201242_s_at 0.0339 ATP1B1 BC000006 ATPase, Na+/K+ transporting, beta 1 polypeptide
55 213388_at 0.0346 PDE4DIP H15535 ym27c01.s1 Soares infant brain 1NIB cDNA clone IMAGE:49385 3'
56 214182_at 0.036 ARF6 AA243143 ADP-ribosylation factor 6
57 212190_at 0.0362 SERPINE2 AL541302 AL541302 Homo sapiens PLACENTA cDNA clone CS0DE006YI10 5'
58* 204015_s_at 0.0365 DUSP4 BC002671 dual specificity phosphatase 4
59** 206366_x_at 0.0372 XCL1 U23772 chemokine (C motif) ligand 1
60* 216609_at 0.0374 TXN AF065241 Thioredoxin
61 219836_at 0.038 ZBED2 NM_024508 zinc finger, BED domain containing 2
62** 208602_x_at 0.0383 CD6 NM_006725 CD6 antigen
63** 208302_at 0.0385 HB-1 NM_021182 minor histocompatibility antigen HB-1
64 209433_s_at 0.0393 PPAT AI457120 phosphoribosyl pyrophosphate amidotransferase
65** 221618_s_at 0.0404 TAF9L AF220509 TAF9-like RNA polymerase II
66 202807_s_at 0.0427 TOM1 NM_005488 target of myb1 (chicken)
67 222145_at 0.043   AK027225 Similar to PI-3-kinase-related kinase SMG-1 isoform 1; (LOC390682)
68** 212599_at 0.0435 AUTS2 AK025298 autism susceptibility candidate 2
69 209392_at 0.0447 ENPP2 L35594 ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)
70 204137_at 0.0453 TM7SF1 NM_003272 transmembrane 7 superfamily member 1 (upregulated in kidney)
71 209015_s_at 0.0455 DNAJB6 BC002446 DnaJ (Hsp40) homolog, subfamily B, member 6
72 209013_x_at 0.0482 TRIO AF091395 triple functional domain (PTPRF interacting)
73 215920_s_at 0.0488 LOC283970 AC002544  
74 221069_s_at 0.0492 LOC51204 NM_016360 clone HQ0477 PRO0477p
75 214741_at 0.0494 ZNF131 AW968301 zinc finger protein 131 (clone pHZ-10)
76 207485_x_at 0.0495 BTN3A1 NM_007048 butyrophilin, subfamily 3, member A1
77 220937_s_at 0.0496 SIAT7D NM_014403 sialyltransferase 7D