Table 1 Baseline characteristics of subjects stratified by ADRB3 genotype
Trp/Trp | Trp/Arg + Arg/Arg | Standardized difference | P value | |
|---|---|---|---|---|
Women (N) | 385 | 61 | ||
Age (y) | 71 ± 8 | 71 ± 6 | 0.00 | 0.47 |
Weight (kg) | 64 ± 12 | 67 ± 13 | 0.25 | 0.08 |
Height (cm) | 160 ± 6 | 160 ± 6 | 0.00 | 0.90 |
BMI (kg/m2) | 25 ± 5 | 26 ± 5 | 0.20 | 0.10 |
Ca intake (mg/day) | 644 ± 372 | 650 ± 355 | 0.02 | 0.90 |
Physical activity (METs) | 80 ± 30 | 82 ± 23 | 0.07 | 0.54 |
Femoral neck BMD (g/cm2) | 0.76 ± 0.13 | 0.79 ± 0.13 | 0.23 | 0.24 |
Lumbar spine BMD (g/cm2) | 1.00 ± 0.18 | 1.04 ± 0.21 | 0.22 | 0.11 |
Age of menopause (y) | 47 ± 7 | 46 ± 7 | -0.14 | 0.52 |
Current/ex smoker a,b | 106 (27.5) | 22 (36.1) | 1.87 | |
Men (N) | 224 | 41 | ||
Age (y) | 70 ± 6 | 68 ± 5 | -0.34 | 0.12 |
Weight (kg) | 78 ± 12 | 77 ± 13 | -0.08 | 0.46 |
Height (cm) | 174 ± 6 | 173 ± 8 | -0.16 | 0.77 |
BMI (kg/m2) | 26 ± 3 | 26 ± 4 | 0.00 | 0.68 |
Ca intake (mg/day) | 657 ± 367 | 732 ± 317 | 0.21 | 0.23 |
Physical activity (METs) | 76 ± 49 | 72 ± 48 | -0.08 | 0.69 |
Femoral neck BMD (g/cm2) | 0.92 ± 0.15 | 0.93 ± 0.15 | 0.07 | 0.63 |
Lumbar spine BMD (g/cm2) | 1.26 ± 0.21 | 1.24 ± 0.24 | -0.09 | 0.59 |
Current/ex smoker a,b | 122 (54.5) | 25 (61.0) | 0.59 |