Table 3 Allele and genotype frequencies of SNPs and their association status with diabetic chronic renal insufficiency.

REN

C>T (-4063)

C = 0.85

C = 0.84

CC = 0.73

CC = 0.72

χ² = 1.01, P = 0.60

χ² = 0.29, P = 0.59

T = 0.15

T = 0.16

CT = 0.24

CT = 0.23

TT = 0.03

TT = 0.05

REN

(ACAG)n

1 = 0.80

1 = 0.81

11 = 0.64

11 = 0.67

χ² = 8.56, P = 0.38 (df = 4)

χ² = 4.55, P = 0.34 (df = 8)

2 = 0.10

2 = 0.105

12 = 0.155

12 = 0.14

3 = 0.09

3 = 0.07

13 = 0.155

13 = 0.10

4 = 0.01

4 = 0.016

14 = 0.02

14 = 0.026

5 = 0.00

5 = 0.005

22 = 0.01

22 = 0.02

23 = 0.02

23 = 0.02

33 = 0.00

24 = 0.005

33 = 0.01

55 = 0.005

AGT

A>G (-6)

G = 0.46

G = 0.41

GG = 0.32

GG = 0.24

χ² = 2.21, P = 0.14

χ² = 3.38, P = 0.18

A = 0.54

A = 0.59

GA = 0.28

GA = 0.34

AA = 0.40

AA = 0.42

AGT

Thr174Met

C = 0.90

C = 0.87

CC = 0.81

CC = 0.76

χ² = 1.32, P = 0.25

χ² = 1.48, P = 0.48

T = 0.10

T = 0.13

CT = 0.18

CT = 0.23

TT = 0.01

TT = 0.01

AGT

Met235Thr

T = 0.61

T = 0.37

TT = 0.42

TT = 0.16

χ² = 46.41, P << 0.01

χ² = 39.2, P << 0.01

C = 0.39

C = 0.63

TC = 0.38

TC = 0.42

CC = 0.20

CC = 0.42

ACE

Ins/Del

Ins = 0.56

Del = 0.44

Ins = 0.53

Del = 0.47

Ins/Ins = 0.34

Ins/Del = 0.43

Del/Del = 0.23

Ins/Ins = 0.34

Ins/Del = 0.38

Del/Del = 0.28

χ² = 0.76, P = 0.38

χ² = 1.60, P = 0.45

AT1

A>C (-1166)

A = 0.93

A = 0.93

AA = 0.86

AA = 0.86

χ² = 0.08, P = 0.78

χ² = 0.20, P = 0.90

C = 0.07

C = 0.07

AC = 0.13

AC = 0.11

CC = 0.01

CC = 0.01

CYP11B2

T>C (-344)

T = 0.64

T = 0.73

TT = 0.40

TT = 0.54

χ² = 8.54, P = 0.003

χ² = 0.84, P = 0.01

C = 0.36

C = 0.27

T C = 0.47

T C = 0.38

CC = 0.13

CC = 0.08

CMA

G>A (-1903)

G = 0.57

G = 0.52

GG = 0.27

GG = 0.13

χ² = 2.51, P = 0.11

χ² = 12.5, P = 0.002

A = 0.43

A = 0.48

GA = 0.62

GA = 0.77

AA = 0.12

AA = 0.10

CMA

C>T (-1777)

C = 0.68

C = 0.71

CC = 0.49

CC = 0.50

χ² = 0.88, P = 0.35

χ² = 4.24, P = 0.12

T = 0.32

T = 0.29

CT = 0.38

CT = 0.43

TT = 0.13

TT = 0.07