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Table 3 Two-point lod scores obtained for 15 markers on chromosome 10 in the South African family with recurrence of arrhythmogenic right ventricular cardiomyopathy. Lod scores were calculated for different values of penetrance (a: 60%; b: 95%)

From: Arrhythmogenic right ventricular cardiomyopathy type 6 (ARVC6): support for the locus assignment, narrowing of the critical region and mutation screening of three candidate genes

  

Recombination fraction

Marker

Penetrance

0.00

0.01

0.05

0.10

0.20

0.30

0.40

D10S465

a

-2.87

-0.94

-0.31

-0.10

0.02

0.01

-0.02

 

b

-3.94

-1.18

-0.54

-0.32

-0.17

-0.13

-0.09

D10S547

a

-6.39

-1.60

-0.34

0.09

0.34

0.31

0.17

 

b

-8.67

-1.11

0.13

0.53

0.70

0.59

0.34

D10S1705

a

0.02

0.02

0.02

0.02

0.02

0.01

0.01

 

b

-0.11

-0.11

-0.08

-0.06

-0.01

0.01

0.01

D10S2325

a

0.91

0.89

0.80

0.68

0.43

0.21

0.05

 

b

1.16

1.14

1.03

0.89

0.60

0.31

0.08

D10S1707

a

1.33

1.31

1.22

1.09

0.83

0.54

0.24

 

b

1.33

1.32

1.26

1.18

0.96

0.69

0.37

D10S1664

a

0.59

0.57

0.51

0.43

0.29

0.16

0.06

 

b

0.70

0.68

0.63

0.56

0.42

0.28

0.13

D10S191

a

2.43

2.38

2.21

1.98

1.49

0.95

0.40

 

b

2.93

2.88

2.68

2.43

1.88

1.26

0.61

D10S1653

a

2.43

2.38

2.21

1.98

1.49

0.95

0.40

 

b

2.93

2.88

2.68

2.43

1.88

1.26

0.61

D10S1477

a

-2.27

-0.20

0.39

0.55

0.55

0.40

0.19

 

b

-3.06

-0.07

0.56

0.75

0.77

0.61

0.35

D10S1661

a

-1.88

0.19

0.73

0.84

0.73

0.48

0.20

 

b

-2.28

0.68

1.21

1.28

1.11

0.77

0.37

D10S504

a

0.93

0.91

0.82

0.71

0.47

0.25

0.08

 

b

1.22

1.20

1.10

0.98

0.72

0.44

0.18

D10S2318

a

0.55

0.54

0.48

0.41

0.26

0.13

0.03

 

b

0.77

0.75

0.68

0.59

0.41

0.22

0.07

D10S548

a

1.0

0.98

0.89

0.77

0.53

0.29

0.10

 

b

1.29

1.26

1.17

1.05

0.79

0.49

0.21

D10S466

a

-2.60

-0.57

0.02

0.20

0.24

0.15

0.06

 

b

-3.38

-0.41

0.19

0.37

0.40

0.29

0.12

D10S245

a

0.55

0.54

0.48

0.41

0.26

0.14

0.04

 

b

0.84

0.82

0.75

0.67

0.48

0.29

0.11