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Table 3 EcN specific expression of selected genes in Caco-2 cells cocultured with inactivated bacteria or bacteria conditioned media for 6 hours.

From: The host response to the probiotic Escherichia coli strain Nissle 1917: Specific up-regulation of the proinflammatory chemokine MCP-1

Gene Inactivated EcN EcN CM
DUSP5 (+) no EcN specific gene regulation
ELF3 (+) no EcN specific gene regulation
MCP-1 no EcN specific gene regulation no EcN specific gene regulation
MIP-2α (+++) no EcN specific gene regulation
MIP-2β (++) no EcN specific gene regulation
NFκBIA no EcN specific gene regulation no EcN specific gene regulation
  1. Gene expression was analyzed by real-time RT-PCR and differences of fold changes for EcN and E. coli MG1655 were compared. EcN specific fold change of Caco-2 cell gene expression (+) between 0.5 and 2, (++) between 2 and 10 and (+++) > 10.