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Table 6 Summary of haplotype scores representing associations between blood pressure and haplotypes in the AIB phase II population showing overall statistical significance values

From: Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians

 

Haplotypes (amino acid)

EVEa

KVGa

KVEa

EMEa

Overall p-val

Daytime DBP

Haplotype scoreb

-0.136

-0.266

0.890

-0.726

0.76

 

Haplotype scoreb (adjusted*)

-0.361

-0.192

0.985

-0.565

0.77

Nighttime SBP

Haplotype scoreb

-0.657

1.676

-0.576

-0.586

0.40

 

Haplotype scoreb (adjusted*)

-0.803

1.676

-0.573

-0.294

0.42

Nighttime DBP

Haplotype scoreb

-1.313

1.313

0.665

-0.699

0.41

 

Haplotype scoreb (adjusted*)

-1.453

1.177

0.706

-0.260

0.47

  1. * Adjusted for age, sex and alcohol intake
  2. a haplotypes defined from positions 128, 257 and 308 respectively
  3. b from the haplo.score method