Table 1 Genotype frequencies and linear regression analysis of the SNPs in TP53 and hCAD genes
Gene | Genotypes | Number (%) | Gene (polymorphism) | R2 | ΔR2 | Unexplained variance (%) | p value | |
|---|---|---|---|---|---|---|---|---|
HD patients | Controls | |||||||
TP53 | GG | 89 (53) | 86 (51) | HD CAG | .308 | - | ||
CG | 69 (41) | 69 (41) | ||||||
CC | 9 (5) | 13 (8) | HD CAG + | |||||
TP53 (R72P) | .314 | .006 | 0.9 | .130 | ||||
hCAD | GG | 141 (84) | ||||||
AG | 23 (14) | HD CAG + | ||||||
AA | 3 (2) | hCAD (R196K) | .305 | .003 | 0.4 | .590 | ||