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Table 5 Allele average effects αS, αM and αL estimated for S, M and L alleles respectively of the 3'VNTR-APOB polymorphism in the whole sample of healthy subjects after normalization for age, sex and BMI (computed according to the formula: BMI = weight [Kg]/ height [m2])

From: A study of the average effect of the 3'APOB-VNTR polymorphism on lipidemic parameters could explain why the short alleles (<35 repeats) are rare in centenarians

 

αS

95% c.i. αS

αM

95% c.i. αM

αL

95% c.i. αL

TC

-5.98

-11.62 ÷ -0.74

+1.67

-0.28 ÷ +3.90

+0.93

-6.20 ÷ +8.13

HDL-C

-0.09

-2.01 ÷ +1.71

-0.08

-0.64 ÷ +0.81

+0.26

-2.51 ÷ +2.30

LDL-C

-4.41

-8.93 ÷ -0.20

+1.28

-0.65 ÷ +3.10

+0.45

-5.70 ÷ +6.82

TG (Log10)

+0.01

-0.02 ÷ +0.03

0.00

-0.01 ÷ +0.01

-0.01

-0.04 ÷ +0.02

  1. TC: serum Total Cholesterol; HDL-C: serum HDL-Cholesterol; LDL-C: serum LDL-Cholesterol; TG: serum Tryglycerides. Average effects are expressed in mg/dL. Confidence intervals (c.i.) are computed by bootstrap (1,000 replications).
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BMC Medical Genetics

ISSN: 1471-2350

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