From: The impact of population heterogeneity on risk estimation in genetic counseling
 |  | AB NE(c) | AB E(d) | BB NE | |||
---|---|---|---|---|---|---|---|
rAB,NE (a) | rAB,E (b) | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | -0.1811 | 0.0244 | -0.1663 | 0.0494 | 0.0066 | 0.0169 |
 | 0.4 | -0.2268 | 0.0274 | -0.2882 | 0.0666 | 0.0251 | 0.0166 |
 | 0.6 | -0.2719 | 0.0314 | -0.4016 | 0.0858 | 0.0810 | 0.0186 |
 | 0.8 | -0.3063 | 0.0343 | -0.5001 | 0.1033 | 0.1284 | 0.0190 |
0.6 | 0.2 | -0.4712 | 0.0487 | -0.3140 | 0.0717 | -0.0684 | 0.0165 |
 | 0.4 | -0.5147 | 0.0528 | -0.4333 | 0.0922 | -0.0450 | 0.0161 |
 | 0.6 | -0.5555 | 0.0568 | -0.5414 | 0.1116 | 0.0141 | 0.0174 |
 | 0.8 | -0.5962 | 0.0607 | -0.6362 | 0.1293 | 0.0652 | 0.0176 |
 |  | BB E | AA NE | AA E | |||
rAB,NE | rAB,E | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | 0.0045 | 0.0373 | 0.0060 | 0.0397 | -0.0022 | 0.0691 |
 | 0.4 | -0.0810 | 0.0364 | 0.0218 | 0.0408 | -0.0551 | 0.0737 |
 | 0.6 | -0.1446 | 0.0373 | 0.0453 | 0.0417 | -0.1048 | 0.0865 |
 | 0.8 | -0.2155 | 0.0392 | 0.0740 | 0.0454 | -0.1584 | 0.1034 |
0.6 | 0.2 | 0.1459 | 0.0441 | -0.0308 | 0.0410 | 0.0891 | 0.0836 |
 | 0.4 | 0.0526 | 0.0399 | -0.0148 | 0.0406 | 0.0348 | 0.0735 |
 | 0.6 | -0.0175 | 0.0383 | 0.0099 | 0.0399 | -0.0175 | 0.0732 |
 | 0.8 | -0.0961 | 0.0373 | 0.0393 | 0.0417 | -0.0730 | 0.0797 |