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Table 5 Odds ratios for AD as a function of the -386G/A P3 promoter polymorphism stratified by the presence or absence of APOE ε4 alleles

From: TP73allelic expression in human brain and allele frequencies in Alzheimer's disease

-386G/A genotype

APOE 4/4

APOE -/4

APOE -/-

AA

1.0

1.0

1.0

AG

0.2; 0.02–2.6

1.2; 0.6–1.9

1.2; 0.9–1.7

GG

0.8; 0.04–16.9

2.3; 1.2–4.8*

1.6; 1.0–2.4*

  1. * p = 0.02 The APOE ε2 and ε3 alleles are designated as (-)
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BMC Medical Genetics

ISSN: 1471-2350

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