Figure 3
From: TP73allelic expression in human brain and allele frequencies in Alzheimer's disease
Activity of allelic variants of the TP73 P3 promoter-luciferase constructs in SK-NSH-N neuroblastoma cells. Values are mean (bars) and standard deviation (vertical lines) of triplicate determinations of firefly luciferase activity, normalized to Renilla luciferase. The promoter confers a strong increase in luciferase expression compared to the vector control, but there is no significant difference between promoter activity of the -386G and -386A alleles in this assay.