Figure 1
From: TP73allelic expression in human brain and allele frequencies in Alzheimer's disease
Map of the 5' TP73 exons showing the SNPs utilized in this study. The arrows represent promoter sequences and the rectangles exons. The region of DNA containing the -386G/A SNP is magnified in the lower panel. The SNP is underlined and the dotted line indicates the variant progesterone receptor binding site (AGTCCT, consensus sequence A/TGTYCT) that overlaps the SNP and becomes non-consensus in the G-allele.