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Table 1 Clinical and biochemical characteristics of study subjects

From: Genetic study of common variants at the Apo E, Apo AI, Apo CIII, Apo B, lipoprotein lipase (LPL) and hepatic lipase (LIPC) genes and coronary artery disease (CAD): variation in LIPC gene associates with clinical outcomes in patients with established CAD

 

CAD subjects (n = 102)

Control subjects (n = 104)

p-value

Age (years)

50.1 ± 5.3

47.5 ± 3.7

<0.02

Sex (M/F)

96/6

89/15

NS

Body Mass Index (kg/m2)

26.9 ± 3.2

26.4 ± 3.7

NS

Smokers (%)

85.2%

52.5%

<0.002

Hypertensive (%)

22.5

14.5

NS

Total cholesterol (mg/dl)

197.3 ± 33.7

199.8 ± 41.7

NS

HDL-cholesterol (mg/dl)

27.6 ± 8.2

38.1 ± 10.2

<0.0001

LDL-cholesterol (mg/dl)

145.6 ± 36.9

119.5 ± 32.9

<0.0001

Total triglycerides (mg/dl)

211.3 ± 63.6

188.1 ± 97.4

<0.0006

APO AI (mg/dl)

107.2 ± 17.5

129.1 ± 23.1

<0.0001

APO B (mg/dl)

117.7 ± 25.5

101.1 ± 24.9

<0.01

APO AII (mg/dl)

38.7 ± 6.4

43.9 ± 9.0

<0.001

APO CII (mg/dl)

4.03 ± 1.4

3.99 ± 1.6

NS

APO CIII (mg/dl)

12.1 ± 2.3

13.1 ± 3.2

<0.008

APO E (mg/dl)

8.6 ± 2.1

10.2 ± 3.3

<0.0001

  1. Data are given as means ± SD. Smokers were those currently smoking at baseline. The statistical analysis of total triglycerides and Lp(a) were performed on log-transformed values, but the untransformed values are given in table. After age-standardisation, continuous variables were compared by t-test and ANOVA, and categorical variables by χ2 test