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Table 2 Power to detect the difference between the genotypic distributions in two populations, assuming a sample of 230 from population 1 (cases) and 400 from population 2 (controls).

From: Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen

P1 P2 P1-P2 POWER
0.030 0.010 0.020 0.95
  0.009 0.021 0.97
  0.008 0.022 0.99
  0.007 0.023 0.99
0.050 0.025 0.025 0.77
  0.023 0.027 0.85
  0.021 0.029 0.92
  0.020 0.030 0.94
0.100 0.057 0.043 0.78
  0.055 0.045 0.82
  0.050 0.050 0.91
0.200 0.130 0.070 0.74
  0.120 0.080 0.86
  0.110 0.090 0.94
  0.100 0.100 0.98
0.300 0.200 0.100 0.80
  0.190 0.110 0.88
  0.180 0.120 0.94
0.400 0.280 0.120 0.79
  0.270 0.130 0.84
  0.250 0.150 0.94
0.500 0.360 0.140 0.77
  0.350 0.150 0.84
  0.330 0.170 0.93
  1. Note: P1, the proportion of homozygous mutants in population 1; P2, the proportion of homozygous mutants in population 2.