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Table 4 Genes with increased and decreased levels of expression in at least 15 of 20 comparisonsbetween 4 mutant MeCP2 expressing LCLs and 5 wild type MeCP2 expressing LCLs

From: Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations

INCREASED     
GenBank Accession Expression In Brain Gene Symbol/UniGene No. Gene Name Function
X15306 x NF-H Neurofilament H intermediate filament
J03600 x ALOX5 Arachidonate 5-lipoxygenase synthesis of leukotrienes
M38690   CD9 CD9 antigen (p24) transmembrane protein
J04076 x EGR2 Early growth response 2 transcription factor
AA873858 x H2BFD H2B histone family, member D compaction of DNA
M81750   MNDA Myeloid cell nuclear differentiation antigen cell specific response to interferon
S81914   IER3 Immediate early response 3 inhibits apoptosis
M33197 x GAPDH Glyceraldehyde-3-phosphate dehydrogenase carbohydrate metabolism
AI761588   Hs.359719   
AF052145 x Hs.159528   
AB020695 x Hs.91662   
DECREASED     
GenBank Accession Expression In Brain Gene Symbol/UniGene No. Gene Name Function
L08177   EBI2 Epstein-Barr virus induced gene 2 G-protein coupled receptor
AW026672   TXNIP Thioredoxin interacting protein upregulated by 1,25-dihydroxyvitamin D-3
AI239716   Hs.344976 Chloride intracellular channel 2 proteina anion transport
AI290954 x Hs.110080 Alpha-2-macroglobina cell growth
AI431931 x Hs.128797   
  1. aIdentified in Celera database