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Figure 4 | BMC Medical Genetics

Figure 4

From: A rare novel mutation in TECTA causes autosomal dominant nonsyndromic hearing loss in a Mongolian family

Figure 4

Sequencing analysis of novel missense mutation in exon 20 of TECTA . A. Agarose gel analysis of PCR product TECTA exon 20. 1:I2; 2:II3; 3:III15; 4: III7;5: IV6; 6: II2;7: II7;8: II5;9: II8;10: III3; 11: III10;12: III21;13: III26;14: III28;15: IV4;16: IV14; 17:IV18. B. Representative Sanger sequencing trace showing heterozygous missense mutation at G6016T (arrow) from patients and control subjects. C. Multi-species alignment of amino acids encoded by exon 20 of TECTA across different vertebrates. The conserved aspartate residue is highlighted in red.

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BMC Medical Genetics

ISSN: 1471-2350

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