Table 4 Different gene significant upregulated GO

Germ cell programmed cell death

32.29

2.80 × 10^-3

Developmental programmed cell death

19.37

8.95 × 10^-3

Protein retention in ER lumen

13.84

1.80 × 10^-2

Germ cell migration

13.45

3.65 × 10^-4

Melanocyte differentiation

9.22

8.27 × 10^-3

Mitotic cell cycle spindle assembly checkpoint

8.81

4.36 × 10^-2

Negative regulation of mitotic metaphase/anaphase transition

8.81

4.36 × 10^-2

Pigmentation during development

8.69

1.14 × 10^-4

Pigment cell differentiation

8.61

1.01 × 10^-2

Antigen processing and presentation of peptide antigen via MHC class I

7.60

1.44 × 10^-2

Positive regulation of calcium ion transport into cytosol

6.46

2.26 × 10^-2

Regulation of calcium ion transport into cytosol

5.57

1.16 × 10^-2

T cell proliferation

4.78

4.95 × 10^-2

Regulation of transforming growth factor beta receptor signaling pathway

4.14

3.15 × 10^-2

Positive regulation of homeostatic process

4.04

3.42 × 10^-2

Response to vitamin A

3.84

4.00 × 10^-2

Pigmentation

3.83

9.50 × 10^-3

Mitotic cell cycle checkpoint

3.75

4.30 × 10^-2

Regulation of calcium ion transport

3.74

5.31 × 10^-3

Extracellular matrix organization

3.73

3.63 × 10^-4

Alcohol biosynthetic process

3.67

4.62 × 10^-2

Regulation of metal ion transport

3.59

3.49 × 10^-3

Leukocyte mediated immunity

3.38

5.04 × 10^-3

Cellular response to insulin stimulus

3.32

1.83 × 10^-2

Regulation of ion transport

3.26

3.51 × 10^-3

Lymphocyte mediated immunity

3.23

2.09 × 10^-2

Response to organic cyclic substance

3.20

1.30 × 10^-3

Response to toxin

3.18

3.98 × 10^-2

Double-strand break repair

3.12

4.23 × 10^-2

Sphingolipid metabolic process

3.01

2.82 × 10^-2

Response to molecule of bacterial origin

3.00

1.70 × 10^-2

Adaptive immune response

2.94

3.16 × 10^-2

Response to lipopolysaccharide

2.94

3.16 × 10^-2

Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

2.94

3.16 × 10^-2

Cellular response to hormone stimulus

2.91

2.77 × 10^-3

Response to insulin stimulus

2.91

1.22 × 10^-2

Membrane lipid metabolic process

2.79

3.91 × 10^-2

Activation of MAPK activity

2.76

4.11 × 10^-2

Immune effector process

2.65

8.66 × 10^-3

Protein processing

2.59

2.27 × 10^-2

Extracellular structure organization

2.57

4.72 × 10^-3

Response to oxidative stress

2.56

4.95 × 10^-3

Positive regulation of MAP kinase activity

2.53

3.86 × 10^-2

Regulation of MAP kinase activity

2.52

1.21 × 102

Amine transport

2.46

2.99 × 10^-2

Camera-type eye development

2.41

4.79 × 10^-2

Carbohydrate biosynthetic process

2.41

4.79 × 10^-2

Protein oligomerization

2.41

7.85 × 10^-3

Protein maturation

2.38

3.54 × 10^-2

Nucleotide biosynthetic process

2.26

1.29 × 102

Nucleobase, nucleoside and nucleotide biosynthetic process

2.17

1.69 × 10^-2

Nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process

2.17

1.69 × 10^-2

Cell proliferation

2.15

2.12 × 10^-4

Muscle organ development

2.14

1.41 × 102

Regulation of neurogenesis

2.14

3.34 × 10^-2

Skeletal system development

2.13

2.21 × 10^-3

Response to peptide hormone stimulus

2.10

4.96 × 10^-2

Transmembrane receptor protein tyrosine kinase signaling pathway

2.02

2.20 × 10^-2

Regulation of nervous system development

2.02

3.63 × 10^-2

Nitrogen compound biosynthetic process

1.99

5.98 × 10^-3

Enzyme linked receptor protein signaling pathway

1.98

4.86 × 10^-3

Response to drug

1.94

3.62 × 10^-2

Blood vessel development

1.84

4.11 × 10^-2

Response to DNA damage stimulus

1.82

1.20 × 10^-2

Induction of apoptosis

1.82

2.14 × 10^-2

Induction of programmed cell death

1.81

2.19 × 10^-2

Positive regulation of apoptosis

1.80

7.74 × 10^-3

Vasculature development

1.80

4.83 × 10^-2

Positive regulation of programmed cell death

1.79

8.09 × 10^-3

Positive regulation of cell death

1.78

8.74 × 10^-3

M phase

1.77

2.70 × 10^-2

Response to hormone stimulus

1.76

1.98 × 10^-2

Response to endogenous stimulus

1.75

1.46 × 10^-2

Cell cycle phase

1.72

1.82 × 10^-2

Response to abiotic stimulus

1.67

3.73 × 10^-2

Protein kinase cascade

1.66

3.89 × 10^-2

Cellular response to stress

1.65

9.67 × 10^-3

Response to organic substance

1.61

5.45 × 10^-3

Phosphorylation

1.57

5.41 × 10^-3

Oxidation reduction

1.57

1.51 × 10^-2

Phosphate metabolic process

1.56

2.49 × 10^-3

Phosphorus metabolic process

1.56

2.49 × 10^-3

Cell cycle process

1.54

2.79 × 10^-2

Protein amino acid phosphorylation

1.50

2.49 × 10^-2

Immune response

1.50

2.35 × 10^-2

Regulation of cell proliferation

1.44

3.02 × 10^-2

Regulation of programmed cell death

1.43

2.88 × 10^-2

Regulation of cell death

1.43

3.01 × 10^-2

Regulation of apoptosis

1.41

3.91 × 10^-2