Gene SNP | Genotype | N | Controls | Type 2 diabetes | OR (9% CI) | P | aOR (95% CI)a | P |
---|---|---|---|---|---|---|---|---|
TCF7L2 rs7903146 | n | 1049 | 375 | 674 | ||||
C/C | 455 | 182 (48.5) | 273 (40.5) | Reference | ||||
C/T | 488 | 165 (44.0) | 323 (47.9) | |||||
T/T | 106 | 28 (7.5) | 78 (11.6) | 1.34 (1.10–1.63) | 0.004 | 1.39 (1.07–1.81) | 0.014 | |
MAF (T) | 0.30 | 0.36 | ||||||
KCNJ11 rs5219 | n | 1052 | 377 | 675 | ||||
A/A | 1051 | 377 (100) | 674 (99.9) | Reference | ||||
A/G | 1 | 0 (0) | 1 (0.1) | |||||
G/G | 0 | 0 (0) | 0 (0) | - | - | |||
MAF (G) | 0.0 | 0.0007 | ||||||
PPARγ rs1801282 | n | 1021 | 365 | 656 | ||||
C/C | 1020 | 365 (100) | 655 (99.8) | Reference | ||||
C/G | 1 | 0 (0) | 1 (0.2) | |||||
G/G | 0 | 0 (0) | 0 (0) | - | - | |||
MAF (G) | 0.0 | 0.0008 | ||||||
CAPN10 rs3792267 | n | 1048 | 375 | 673 | ||||
G/G | 826 | 289 (77.1) | 537 (79.8) | Reference | ||||
G/A | 209 | 80 (21.3) | 129 (19.2) | |||||
A/A | 13 | 6 (1.6) | 7 (1.0) | 0.85 (0.64–1.12) | 0.25 | 0.70 (0.47–1.03) | 0.07 | |
MAF (A) | 0.13 | 0.11 | ||||||
CAPN10 rs3842570 | n | 1048 | 374 | 674 | ||||
2 repeats/2 repeats | 622 | 225 (60.2) | 397 (58.9) | Reference | ||||
2 repeats/3 repeats | 376 | 128 (34.2) | 248 (36.8) | |||||
3 repeats/3 repeats | 50 | 21 (5.6) | 29 (4.3) | 1.00 (0.80–1.24) | 0.99 | 1.12 (0.84–1.49) | 0.45 | |
MAF (3 repeats) | 0.23 | 0.23 | ||||||
CAPN10 rs5030952 | n | 1048 | 374 | 674 | ||||
C/C | 219 | 79 (21.1) | 140 (20.8) | Reference | ||||
C/T | 523 | 182 (48.7) | 341 (50.6) | |||||
T/T | 306 | 113 (30.2) | 193 (28.6) | 0.98 (0.81–1.17) | 0.79 | 0.98 (0.76–1.25) | 0.84 | |
MAF (T) | 0.55 | 0.54 |