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Table 4 Association of SNPs with P<0.05 for sensitization to allergens in the Chinese population

From: Investigating highly replicated asthma genes as candidate genes for allergic rhinitis

Gene

SNP ID

Chromosome position

Kruskal-Wallis test

B.tropicalis

D. pteronyssinus

SPINK5

rs10477360

5

147384474

0.027

(0.65)

0.69

(1.0)

ADRB2

rs2163752

5

148125331

0.027

(0.65)

0.054

(0.92)

ADRB2

rs30306

5

148132557

0.028

(0.65)

0.074

(0.97)

ADRB2

rs30325

5

148143517

0.27

(0.82)

0.010

(0.52)

ADRB2

rs30328

5

148146640

0.28

(0.82)

0.025

(0.75)

ADRB2

rs30330

5

148148525

0.32

(0.82)

0.027

(0.75)

ADRB2

rs9285673

5

148153121

0.049

(0.78)

0.90

(1.0)

ADRB2

rs10075995

5

148273622

0.53

(0.82)

0.014

(0.52)

NPSR1/AAA1

rs2058163

7

34301616

0.049

(0.78)

0.025

(0.75)

NPSR1/AAA1

rs1419842

7

34321625

0.41

(0.82)

0.031

(0.75)

NPSR1/AAA1

rs2392268

7

34380952

0.44

(0.82)

0.031

(0.75)

NPSR1/AAA1

rs6947789

7

34417405

0.018

(0.65)

0.83

(1.0)

NPSR1/AAA1

rs736295

7

34417742

0.054

(0.79)

0.039

(0.75)

NPSR1

rs2530545

7

34663665

0.94

(0.90)

0.040

(0.75)

NPSR1

rs11761197

7

34666914

0.78

(0.90)

0.013

(0.52)

NPSR1

rs1379928

7

34667814

0.51

(0.82)

0.0098

(0.52)

NPSR1

rs2609224

7

34672931

0.62

(0.85)

0.011

(0.52)

NPSR1

rs2609220

7

34676579

0.68

(0.86)

0.0067

(0.52)

NPSR1

rs2531841

7

34686074

0.81

(0.90)

0.012

(0.52)

NPSR1

rs1419837

7

34692064

0.88

(0.90)

0.018

(0.62)

NPSR1

rs1419779

7

34779833

0.21

(0.82)

0.0011

(0.15)

NPSR1

rs324978

7

34780857

0.20

(0.82)

0.00098

(0.15)

NPSR1

rs1859409

7

34906409

0.049

(0.78)

0.83

(1.0)

NPSR1

rs4723388

7

34909345

0.0056

(0.51)

0.52

(0.98)

NPSR1

rs1186717

7

34937434

0.33

(0.82)

0.036

(0.75)

NPSR1

rs1637673

7

34964375

0.15

(0.82)

0.0081

(0.52)

NPSR1

rs4236340

7

34976719

0.0061

(0.51)

0.46

(0.98)

NPSR1

rs328902

7

34987368

0.41

(0.82)

0.038

(0.75)

NPSR1

rs328906

7

34990440

0.0080

(0.51)

0.58

(0.98)

NPSR1

rs2023328

7

34998155

0.0053

(0.51)

0.60

(0.98)

NPSR1

rs329240

7

35024965

0.41

(0.82)

0.038

(0.75)

MS4A2

rs540170

11

59636614

0.049

(0.78)

0.98

(1.0)

MS4A2

rs581133

11

59638882

0.043

(0.78)

0.99

(1.0)

NOS1

rs1093325

12

116179703

0.031

(0.7)

0.23

(0.98)

NOS1

rs1004356

12

116261755

0.026

(0.65)

0.43

(0.98)

IL4R

rs3024585

16

27267345

0.0036

(0.51)

0.98

(1.0)

IL4R

rs1805011

16

27281373

0.011

(0.51)

0.076

(0.97)

IL4R

rs1805012

16

27281465

0.011

(0.51)

0.076

(0.97)

IL4R

rs1805015

16

27281681

0.022

(0.65)

0.11

(0.97)

IL4R

rs3024685

16

27284411

0.045

(0.78)

0.21

(0.98)

IL4R

rs4787956

16

27285750

0.0087

(0.51)

0.17

(0.97)

IL4R

rs4787426

16

27292232

0.026

(0.65)

0.37

(0.98)

ADAM33

rs512625

20

3596378

0.017

(0.65)

0.22

(0.98)

ADAM33

rs2853210

20

3606211

0.046

(0.78)

0.0010

(0.15)

  1. Association between genotype and sensitization to allergens was analyzed using a Kruskal-Wallis rank sum test. False discovery rate was quantified using the q-value introduced by Storey(2002) and are given in parenthesis.