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Table 3 Descriptive analysis of the β S -haplotypes interference in the phenotypic expression of SCA patients

From: Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia

  Parameters
  Hb F (%) TBARS (ng/mL) TEAC (mM) GST (U/mL) CAT (U/mL) GSH (μM)
Haplotypes (+HU) n       
Bantu/Bantu 2 1.95 1201.18 2.17 1.26 1742.95 1.30
Bantu/Benin 6* 17.42 1066.26 2.03 1.50 2294.01 0.62
Benin/Benin 1 5.2 1616.62 2.17 1.44 2278.17 1.10
Benin/Camer 0 ----- ----- ----- ----- ----- -----
Bantu/Atp1 0 ----- ----- ----- ----- ----- -----
Benin/Atp1 1 1.8 1524.30 2.20 1.20 1531.69 0.19
Benin/Atp2 1 8.4 1012.00 2.01 2.00 1084.51 0.22
Benin/Atp3 1 7.3 1216.92 2.10 1.92 1880.28 0.88
Atp2/Atp2 1 11 1308.00 1.97 1.51 1866.20 0.37
Haplotypes (−HU)
Bantu/Bantu 6* 6.78 2284.33 1.93 2.03 1656.10 0.77
Bantu/Benin 4* 6.68 1815.50 2.09 1.27 1842.43 0.84
Benin/Benin 1 2.1 1222.00 2.09 1.65 2570.42 0.74
Benin/Camer 1 4.8 934.00 1.90 2.00 996.48 0.70
Bantu/Atp1 1 3.2 1287.00 1.95 1.18 2017.61 0.87
Benin/Atp1 0 ----- ----- ----- ----- ----- -----
Benin/Atp2 0 ----- ----- ----- ----- ----- -----
Benin/Atp3 0 ----- ----- ----- ----- ----- -----
Atp2/Atp2 2 7.45 1576.00 1.77 1.45 1248.24 0.32
  1. (+HU): patients treated with HU; (−HU): patients not treated with HU; Camer: Cameroon; Atp: atypical.
  2. *Subgroups subject to statistical comparisons.