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Table 4 Frequency distribution of haplotypes and their association with rickets in cases and controls

From: Relationship between polymorphisms in vitamin D metabolism-related genes and the risk of rickets in Han Chinese children

Gene

Haplotypea

Case (%)

Control (%)

P value

GC

ACT

0.469

0.410

0.1205

CAT

0.229

0.329

0.005 △

ACG

0.288

0.249

0.2452

CYP2R1

GAA

0.352

0.437

0.0261 △

AGG

0.409

0.340

0.06

GGG

0.238

0.213

0.4281

DHCR7/NADSYN1

TG

0.508

0.503

0.9066

 

GA

0.298

0.258

0.2352

 

GG

0.187

0.230

0.1867

  1. aLoci of tag SNPs are written 3′ to 5′ and include the following SNPs: rs4588, rs7041 and rs2282679 in GC, rs12704714, rs10741657 and 2060793 in CYP2R1 and rs3829251 and rs12785878 in DHCR7/NADSYN1.
  2. △Significant P values are indicated by a triangle (△ P<0.05).
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BMC Medical Genetics

ISSN: 1471-2350

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