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Table 3 Results of overall and stratified analyses for the association of XRCC1 399 G → A and risk of glioma, Yosunkaya et al.[34]excluded

From: Association between XRCC1polymorphism 399 G->A and glioma among Caucasians: a systematic review and meta-analysis

Stratification factor

No. of studies

I 2(%)

Odds ratio

95% Confidence interval

P value

Overall

5

7

1.10

0.98-1.23

0.10

Gender

 Male

1

NA

0.94

0.62-1.44

0.78

 Female

1

NA

2.27

1.45-3.57

< 0.001

Glioma Subtype

 Grade III

2

0

1.05

0.89-1.25

0.56

 Grade IV

2

46

1.20

0.97-1.47

0.09

Sample size

 < 500

1

NA

1.61

0.93-2.78

0.09

 ≥ 500

4

0

1.08

0.96-1.21

0.19

Country

 US

3

8

1.11

0.94-1.31

0.22

 Other

2

53

1.09

0.94-1.27

0.26

Genotyping method

 PCR-RFLP

3

27

1.06

0.93-1.21

0.40

 Other

2

0

1.19

0.97-1.46

0.09