Table 2 Patients’ and healthy controls’ characteristics

female/male

264/150

179/94

85/56

264/150

♀ (%)

(63.77 %)

(65.56%)

(60.3%)

(63.77 %)

Age, yy ± SD

42.0±11.0

38.5±9.51

48.5±10.40*

42.0±11.0

(range)

(16.0-72.0)

(17.0-70.0)

(16.0-72.0)

(16.0-72.0)

onset, yy ± SD

32.37±10.37

31.65±10.31

33.17±10.21

-- --

(range)

(11.0-61.0)

(14.0-61.0)

(11.0-55.0)

Duration, yy ± SD

9.14±7.43

6.92±6.47

13.44±7.34*

-- --

(range)

(0.2-50.0)

(0.2-50.0)

(0.2-35.0)

EDSS ± SD

2.91±2.24

1.8±1.04

5.03±2.43*

-- --

(range)

(1.0-10.0)

(1.0-7.0)

(1.0-10.0)

PI ± SD

0.63±1.08

0.59±0.94

0.72±1.32*

-- --

(range)

(0.03-10.0)

(0.03-10.0)

(0.04-10.0)

MSSS ± SD

3.94±2.74

2.93±1.99

5.98±2.87*

-- --

(range)

(0.13-9.99)

(0.13-9.6)

(0.29-9.99)