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Table 1 Association test results for rs11571836 and CVD (SHARE + AP)

From: BRCA2 Variants and cardiovascular disease in a multi-ethnic study

Ethnicity

Individuals with at least one CVD event (% of total)

Individuals with no CVD events (n)

MAF (G allele)*

OR (95% CI)

P

All combined+

115 (10%)

1063

range: 0.15-.038

0.56

0.009

Aboriginal

55 (19%)

235

0.15

0.42 (0.19-0.91)

0.017

South Asian

32 (10%)

291

0.23

0.43 (0.19-0.99)

0.021

European

20 (8%)

245

0.20

0.37 (0.08-1.63)

0.19

Chinese

8 (3%)

292

0.38

0.99 (0.35-2.9)

0.99

  1. + meta-analysis (fixed-effect model) adjusted for multiple comparisons.
  2. *MAF calculated from cases and controls combined for each ethnicity.