c.453-397 T > C | c.30 T > C | |||||||
---|---|---|---|---|---|---|---|---|
AsC | HBV-ALF | P value | OR (95%CI) | AsC | HBV-ALF | P value | OR (95%CI) | |
Men only. | n = 510 | n = 298 | n = 510 | n = 298 | ||||
TT | 193(37.8) | 94(31.5) | 233(457) | 121(40.6) | ||||
TC | 263(51.6) | 149(50.0) | 230(45.1) | 131(43.9) | ||||
CC | 54(10.6) | 55(18.5) | 0.003 | 1.39(1.12-1.73) | 47(9.2) | 46(15.4) | 0.026 | 1.47(1.06-2.17) |
T allele | 649(63.6) | 337(56.5) | 696(68.2) | 373(62.6) | ||||
C allele | 371(36.4) | 259(43.5) | 0.005 | 324(31.8) | 223(37.4) | 0.022 | ||
Women only | n = 347 | n = 61 | n = 347 | n = 61 | ||||
TT | 137(39.5) | 15(24.6) | 185(53.3) | 22(36.1) | ||||
TC | 161(46.4) | 33(54.1) | 118(34.0) | 29(47.5) | ||||
CC | 49(14.1) | 13(21.3) | 0.022 | 1.56(1.08-2.35) | 44(12.7) | 10(16.4) | 0.037 | 1.63(1.07-2.47) |
T allele | 435(62.7) | 63(51.6) | 488(70.3) | 73(59.8) | ||||
C allele | 259(37.3) | 59(48.4) | 0.021 | 206(29.7) | 49(40.2) | 0.021 | ||
Age ≥ 40 y | n = 277 | n = 166 | n = 277 | n = 166 | ||||
TT | 118(42.6) | 54(32.5) | 151(54.5) | 71(42.8) | ||||
TC | 135(48.7) | 83(50.0) | 101(36.5) | 74(44.6) | ||||
CC | 24(8.7) | 29(17.5) | 0.008 | 1.83(1.21-2.63) | 25(9.02) | 21(12.7) | 0.041 | 1.62(1.08-2.54) |
T allele | 371(67.0) | 191(57.5) | 403(72.7) | 216(65.1) | ||||
C allele | 183(33.0) | 141(42.5) | 0.005 | 151(27.3) | 116(34.9) | 0.0003 | ||
Age < 40 y | n = 580 | n = 193 | n = 580 | n = 193 | ||||
TT | 212(36.6) | 55(28.5) | 267(46.0) | 72(37.3) | ||||
TC | 289(49.8) | 99(51.3) | 247(42.6) | 86(44.6) | ||||
CC | 79(13.6) | 39(20.2) | 0.036 | 1.35(1.09-2.21) | 66(11.4) | 35(18.1) | 0.024 | 1.54(1.07-1.98) |
T allele | 713(61.5) | 209(54.1) | 781(68.2) | 230(59.6) | ||||
C allele | 447(38.5) | 177(45.9) | 0.011 | 369(31.8) | 156(40.4) | 0.003 |