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Figure 4 | BMC Medical Genetics

Figure 4

From: The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy

Figure 4

Methylation status of the B promoter CpG islands in heart ventricle and atrium. A) Schematic representation of the B isoform (Dp427c) promoter. Grey arrow indicates the transcription start site of the Dp427c mRNA. The DNA sequence and distribution of the CG dinucleotides is shown B) Prediction of the putative CpG island in the B promoter using the Emboss CpGplot algorithm C) Percentage of methylated cytosines within the putative CpG island in DNA extracted from ventricle and atrium muscle tissue, respectively.

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