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Figure 3 | BMC Medical Genetics

Figure 3

From: The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy

Figure 3

Non-radioactive in-situ RNA hybridization on cryosections obtained from the left ventricle of an explanted human heart. Isoform-specific RNA probes recognized the 5' UTR region and first exon of B and M isoforms. The M antisense probe (M9 top right) displayed an intense signal of hybridization whereas the B antisense probe failed to hybridize (B4 top left). Both the M (M10 bottom right) and B sense (B5 bottom left) probes failed to hybridize.

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BMC Medical Genetics

ISSN: 1471-2350

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