| Â | Controls(N = 426) | Cases(N = 545) | Â | Â | Â | Â |
|---|
NAT2 Phenotype | n | % | n | % | OR | CI | p | q |
|---|
Slow
| 241 | 56.6 | 299 | 54.9 | 1 | - | - | - |
Intermediate
| 161 | 37.8 | 198 | 36.4 | 0.993 | 0.76-1.31 | 0.959 | 0.959 |
Rapid
| 19 | 4.5 | 42 | 7.7 | 1.82 | 1.04-3.30 | 0.042a | 0.084 |
- Logistic regression analysis of individual NAT2 phenotypes, adjusted for age OR = odds ratio, CI = 95% confidence intervals for ORs, p = p-value, q = q-values for multiple testing adjustment using Holm's method. aWhen intermediate and slow phenotypes are combined (due to p = 0.96) and used as reference, the p-value for rapid is 0.037, and no multiple testing correction is needed since it is a single hypothesis
