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Table 5 Comparisons Between NAT2 Phenotypes

From: Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study

  Controls(N = 426) Cases(N = 545)     
NAT2 Phenotype n % n % OR CI p q
Slow 241 56.6 299 54.9 1 - - -
Intermediate 161 37.8 198 36.4 0.993 0.76-1.31 0.959 0.959
Rapid 19 4.5 42 7.7 1.82 1.04-3.30 0.042a 0.084
  1. Logistic regression analysis of individual NAT2 phenotypes, adjusted for age OR = odds ratio, CI = 95% confidence intervals for ORs, p = p-value, q = q-values for multiple testing adjustment using Holm's method. aWhen intermediate and slow phenotypes are combined (due to p = 0.96) and used as reference, the p-value for rapid is 0.037, and no multiple testing correction is needed since it is a single hypothesis