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Table 1 Characteristics of PSP Cases and Controls

From: Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study

  Case (N = 545)a Control (N = 426)
  n % n % p
Gender      0.490
Female 266 49 197 47  
Male 279 51 226 53  
Race      --
Caucasian 545 100 426 100  
Age b      < 0.001
Median(Min, Max) 76(44,98)   73(33,92)   
Mean(SD) 75.4(8.0)   72(10.7)   
Clinical Diagnosis      
PSP 468 87    
Otherc 68 13    
Falls      
Yes 482 99    
No 3 1    
Dementia      
Yes 278 82    
No 62 18    
Eye Mov. Abn.      
Yes 349 96    
No 13 4    
Rigidity      
Yes 374 98    
No 9 2    
Instability      
Yes 454 99    
No 4 1    
Dysarthria      
Yes 370 97    
No 10 3    
Dysphagia      
Yes 352 92    
No 31 8    
AD Path.      
Yes 50 9    
No 495 91    
Family History      
Yes 322 73    
No 121 27    
  1. aNs of cases for characteristics including and following "clinical diagnosis" may not total 545 as information for these variables was not available for every case.% represent% of those with data. bAge represents age at death for cases and age at blood draw for controls. cOther clinical diagnoses included Alzheimer disease, Parkinson's disease, corticobasal degeneration, multiple system atrophy, Parkinson's disease with dementia, vascular dementia, progressive non-fluent aphasia and dementia. Abbreviations: p = p-value (chi-squared), Eye Mov. Abn. = eye movement abnormalities, AD Path. = presence of coexisting Alzheimer's pathology