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Table 1 Characteristics of PSP Cases and Controls

From: Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study

 

Case (N = 545)a

Control (N = 426)

 

n

%

n

%

p

Gender

    

0.490

Female

266

49

197

47

 

Male

279

51

226

53

 

Race

    

--

Caucasian

545

100

426

100

 

Age b

    

< 0.001

Median(Min, Max)

76(44,98)

 

73(33,92)

  

Mean(SD)

75.4(8.0)

 

72(10.7)

  

Clinical Diagnosis

     

PSP

468

87

   

Otherc

68

13

   

Falls

     

Yes

482

99

   

No

3

1

   

Dementia

     

Yes

278

82

   

No

62

18

   

Eye Mov. Abn.

     

Yes

349

96

   

No

13

4

   

Rigidity

     

Yes

374

98

   

No

9

2

   

Instability

     

Yes

454

99

   

No

4

1

   

Dysarthria

     

Yes

370

97

   

No

10

3

   

Dysphagia

     

Yes

352

92

   

No

31

8

   

AD Path.

     

Yes

50

9

   

No

495

91

   

Family History

     

Yes

322

73

   

No

121

27

   
  1. aNs of cases for characteristics including and following "clinical diagnosis" may not total 545 as information for these variables was not available for every case.% represent% of those with data. bAge represents age at death for cases and age at blood draw for controls. cOther clinical diagnoses included Alzheimer disease, Parkinson's disease, corticobasal degeneration, multiple system atrophy, Parkinson's disease with dementia, vascular dementia, progressive non-fluent aphasia and dementia. Abbreviations: p = p-value (chi-squared), Eye Mov. Abn. = eye movement abnormalities, AD Path. = presence of coexisting Alzheimer's pathology