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Table 2 Allelic expression analysis for 33 patients

From: Allelic expression analysis of the osteoarthritis susceptibility locus that maps to MICAL3

       BCL2L13    BID      MICAL3    
Patient no. Sex Age at surger y (years) Tissue* rs4488761 rs2587100 rs9967 rs11538 rs2277831 rs5992854 rs11917 rs1057721 rs4819639
     Gen^ AER† (A/G) Gen^ AER† (C/G) Gen^ AER† (C/T) Gen^ AER† (T/C) Gen^ Gen^ AER† (T/C) Gen^ AER† (T/G) Gen^ AER† (G/A) Gen^ AER† (C/T)
1 F 55 Cart (K) AG 1.04 CG 0.67 CT 0.71 TC 0.90 GG CC - GG - AA - CC -
33 M 74 Cart (K) AG 1.15 CG 1.03 CT 0.91 TT - GG CC - GG - AA - CC -
3 M 82 Cart (K) AA - CG 0.83 TT - TC 1.10 GA TC 1.13 GG - AA - CT 0.96
4 M 57 Cart (K) AG 0.95 CG 0.87 CT 1.09 TC 1.06 GA TC 0.56 TG 1.30 GA 2.10 CT 1.38
34 F 57 Cart (K) AA - GG - TT - TT - GA TC 1.14 TG 0.88 GA 0.84 CT 0.90
35 M 58 Cart (K) AA - CG 0.78 TT - TT - GA TC 1.30 TG 1.11 GA 0.87 CT 1.02
36 M 71 Cart (K) GG - GG - CC - TT - GA TC 1.02 GG - AA - CC -
37 F 72 Cart (K) AG 1.09 CG 0.91 CT 1.15 TC 1.54 AA TT - TG 1.51 GA 0.85 CT 0.87
38 M 64 Cart (K) AG 0.91 CG 1.01 CT 1.09 TT - AA TC 5.47 TT - GG - CC -
39 M 76 Cart (K) GG - CG 0.88 CT 1.33 TT - AA TT - TG 1.01 GA 1.51 CT 0.82
13 F 66 Cart (K) AG 1.40 CG 2.82 CT 0.57 TT - AA TC 1.22 TT - GG - TT -
26 F 67 Cart (H) AG 1.67 CG 1.98 CT 1.01 TT - AA TC 0.83 TT - GG - TT -
40 F 76 Cart (H) AG 1.04 CG 0.99 CT 1.22 TC 1.01 AA TT - TG 0.76 GA 1.14 CT 1.49
41 F 50 Cart (H) GG - CG 0.94 CC - TT - AA TT - TT - GG - CT 0.83
42 M 83 Cart (H) AG 0.97 CG 1.00 CT 1.18 TC 0.96 AA TC 1.03 TG 1.00 GA 1.16 CT 0.93
43 M 62 Fat pad AG 1.06 CG 1.00 CT 1.01 TC 0.94 GG CC - TG 1.09 GA 1.39 CC -
44 M 57 Fat pad AG 1.01 GG - CT 0.80 TT - GG TT - GG - AA - CC -
45 M 76 Fat pad GG - GG - CC - TT - GA TC 1.92 GG - AA - CC -
46 M 79 Fat pad GG - GG - CC - TT - GA TC 0.96 TG 1.03 GA 1.13 CT 1.02
47 M 58 Fat pad AG 0.99 CC - TT - TT - GA TT - GG - AA - CC -
48 M 58 Fat pad AG 1.02 CG 1.00 CT 1.36 TT - AA TT - TG 0.80 GA 0.63 CT 1.09
49 F 42 Fat pad AG 1.05 CG 0.94 CT 1.15 TT - AA TT - TG 2.13 GA 1.22 CT 0.92
50 M 71 Fat pad GG - CG 1.00 CT 1.13 TT - AA TT - TG 1.27 GA 1.23 CC -
51 F 67 Fat pad AG 0.95 CG 1.05 CT 0.95 TT - AA TC 0.75 TT - GG - TT -
52 F 78 Fat pad AG 1.15 CG 0.89 CT 0.92 TT - AA TT - GG - AA - CC -
53 M 74 Syn AG 0.80 GG - CT 1.33 TT - GG CC - GG - AA - CC -
54 M 62 Syn AG 0.99 CG 0.85 CT 1.23 TT - GA TC 1.12 GG - AA - CC -
55 M 67 Syn AG 0.97 CG 0.98 CT 1.32 TC 0.83 GA TC 0.81 TG 0.57 GA 0.75 CT 1.24
56 M 60 Syn AG 1.11 GG - CT 1.14 TT - AA TT - TG 1.19 GA 1.32 CC -
57 M 69 Syn AG 0.85 CG 1.98 CT 0.72 TC 2.09 AA TT - TT - GG - CT 0.77
58 F 54 Syn AG 0.90 CG 1.16 CT 1.19 TC 1.56 AA TT - TG 1.85 GA 1.89 CC -
52 F 78 Syn AG 1.00 CG 0.95 CT 1.02 TT - AA TT - GG - AA - CC -
59 F 72 Can bn AA - CG 1.10 TT - TC 1.14 GA TC 0.96 TG 0.86 GA 1.23 CT 1.07
60 M 86 Can bn GG - GG - CC - TT - AA TT - TG 1.43 GA 1.10 CC -
60 M 86 OP GG - GG - CC - TT - AA TT - TG 1.27 GA 1.31 CC -
  1. *Cart (H), hip cartilage; Cart (K), knee cartilage; Syn, synovium; Can bn, cancellous bone;
  2. OP, osteophyte
  3. ^Gen, genotype
  4. †AER, allelic expression ratio
  5. Bold text denotes allelic expression imbalance (AEI) at the 20% threshold.