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Table 1 Characteristics of the study subjects

From: The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study

 

All subjects

T2DM

Control

P-value

 

n = 6094

n = 333

n = 417

 

Age (years)

49.9 ± 8.3

54.4 ± 6.4

53.7 ± 5.1

0.19

BMI (kg/m2)

23.7 ± 3.0

25.0 ± 3.6

23.1 ± 2.7

< 0.0001

SBP (mmHg)

119.9 ± 15.1

126.3 ± 15.6

120.2 ± 16.2

< 0.0001

DBP (mmHg)

76.6 ± 11.4

79.7 ± 11.0

76.6 ± 11.8

0.0004

Total-cholesterol (mg/dl)

211.9 ± 33.9

212.7 ± 35.0

211.1 ± 31.9

0.77

LDL-cholesterol (mg/dl)

130.0 ± 30.2

131.2 ± 29.8

130.3 ± 29.9

0.65

HDL-cholesterol (mg/dl)

57.8 ± 16.3

54.0 ± 16.1

58.7 ± 16.4

0.0002

Triglyceride (mg/dl)

140.0 ± 107.0

160.5 ± 146.7

134.9 ± 110.6

0.012*

Glucose (mg/dl)

100.5 ± 19.8

153.8 ± 40.7

91.8 ± 4.9

< 0.0001*

HbA1c (%)

5.3 ± 0.76

7.3 ± 1.5

5.1 ± 0.33

< 0.0001

T2DM (%)

6.2

100

0

-

Obesity (BMI ≧ 30) (%)

2.6

6.9

1.0

< 0.0001

Overweight (BMI ≧ 25) (%)

27.0

37.8

21.6

< 0.0001

Hypertension (%)

13.5

29.3

13.2

0.0004

Current smorker (%)

39.8

44.6

41.4

0.62

  1. *Statistical test for triglyceride and glucose levels were calculated on log-transformed values
  2. P-values between T2DM and contol groups were calculated by t-test or χ 2-test
  3. Data are expressed as mean ± SD or percentage