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Table 5 Clinical and laboratory dataa (UCP-1 rs6536991 genotype)

From: The contribution of FTO and UCP-1SNPs to extreme obesity, diabetes and cardiovascular risk in Brazilian individuals

 

Age (years)

Weight (Kg)

Height (cm)

Waist (cm)

BMI (kg/m2)

HDL (mg/dl)

LDL (mg/dl)

TG (mg/dl)

SBP (mmHg)

DBP (mmHg)

Fasting Glucose (mg/dl)

Obese

           

TT

40.5±9.5

124.2±29.4

164.3±10.1

124.6±17.5

45.6±7.8

47.2±6.2

113.1±30.1

142.1±48.1

131±8.7

83.5±6.7

98.5±15.8

 

(33.7-47.3)

(103.2-145.2)

(157.1-171.5)

(112.1-137.1)

(40–51.2)

(42.7-51.7)

(91.6-134.6)

(107.7-176.5)

(124.7-137.3)

(78.7-88.3)

(87.2-109.8)

TC

39.8±12.6

114.6±20.9

163.6±8.8

119.7±12

42.6±5.8

50.6±13.2

119.6±35.7

154.0±96.7

137.4±14.1

87.2±8.7

107.7±48.6

 

(37.1-42.5)

(110.2-119.1)

(161.8-165.5)

(117.1-122.3)

(41.4-43.8)

(47.8-53.5)

(111.8-127.4)

(132.8-175.1)

(134.4-140.4)

(85.3-89)

(97.1-118.3)

CC

41.9±14.2

113.0±20

162.4±8.9

116.5±14.7

42.7±4.7

54.4±10.7

129.3±32.1

145.4±85.7

133.4±14.5

85.7±8.9

98.9±23.2

 

(36.5-47.3)

(105.4-120.6)

(159–165.8)

(111–122.1)

(40.9-44.5)

(50.1-58.6)

(116.6-142)

(112.2-178.7)

(127.9-138.9)

(82.3-89.1)

(89.9-107.9)

Control

           

TT

51.2±16.3

64.0±9.7

161.0±6.1

85.8±11.2

24.7±3.4

54.8±15

134.1±39.1

127.5±52.4

135.7±21.7

81.6±6.3

80.0±12.6

 

(42.9-59.6)

(59–69)

(157.8-164.2)

(78.6-93)

(22.9-26.4)

(46.1-63.5)

(111.5-156.7)

(97.2-157.8)

(124.5-146.9)

(78.4-84.9)

(72.7-87.2)

TC

52.1±15

58.0±9.7

158.4±8

81.2±17.8

23.0±3.1

42.3±11.4

133.4±35.8

157.6±67.7

134.2±17.8

83.3±9.2

91.1±27.3

 

(47.5-56.8)

(55–61.1)

(155.9-160.9)

(77.5-84.9)

(22.1-24)

(38.3-46.2)

(121.6-145.2)

(135.3-179.8)

(128.7-139.8)

(80.4-86.2)

(82.1-100.1)

CC

48.0±19.3

56.6±10.7

161.6±9.8

74.4±11.6

21.7±3.5

49.3±16.4

113.1±25.6

110.4±59.5

126.9±15.7

80.1±9.1

89.3±14.9

 

(42.7-53.3)

(53.7-59.5)

(158.9-164.2)

(70.6-78.2)

(20.7-22.6)

(43.8-54.9)

(104.4-121.8)

(90.3-130.5)

(112.7-131.2)

(77.6-82.6)

(84.4-94.2)

  1. aData shown as average ± SD and 95% confidence interval of the mean; bBMI, Body Mass Index; cHigh Density Lipoprotein; dLDL, Low Density Lipoprotein; eTG, Triglycerides; fSBP, Systolic Blood Pressure; gDBP, Diastolic Blood Pressure. TT denotes homozygous carriers of the T allele, TC heterozygous carriers, and CC noncarriers of UCP-1 rs6536991.
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BMC Medical Genetics

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