Table 4 Genotype distribution in relation to sub sites in colorectal cancer
Genotypes | controls | Colon cancer | Rectal cancer | ||
|---|---|---|---|---|---|
| Â | n (%) | n (%) | OR(95% CI)a | n(%) | OR (95% CI)a |
rs266729 | Â | Â | Â | Â | Â |
CC | 243(43.78) | 68(35.60) | Reference | 105(45.85) | Reference |
GC | 261(47.03) | 107(56.02) | 1.50(1.05,2.14) | 98(42.79) | 0.88(0.63,1.22) |
GG | 51(9.19) | 16(8.38) | 1.19(0.64,2.25) | 26(11.35) | 1.20(0.71,2.04) |
GC/GG | 312(56.22) | 123(64.40) | 1.45(1.03, 2.05) | 124(54.15) | 0.94(0.69,1.28) |
rs822395 | Â | Â | Â | Â | Â |
AA | 440(79.28) | 155(81.15) | Reference | 188(82.10) | Reference |
AC | 109(19.64) | 32(16.75) | 0.82(0.53,1.27) | 38(16.59) | 0.80(0.53,1.20) |
CC | 6(1.08) | 4(2.09) | 1.63(0.45,5.97) | 3(1.31) | 1.25(0.31,5.06) |
AC/CC | 115(20.72) | 36(18.85) | 0.86(0.56,1.31) | 41(17.90) | 0.82(0.55,1.22) |
rs822396 | Â | Â | Â | Â | Â |
AA | 450(81.08) | 161(84.29) | Reference | 183(79.91) | Reference |
AG | 99(17.84) | 28(14.66) | 0.830(0.52,1.31) | 45(19.65) | 1.11(0.75,1.65) |
GG | 6(1.08) | 2(1.05) | 0.93(0.18,4.70) | 1(0.44) | 0.38(0.05,3.17) |
AG/GG | 105(18.92) | 30(15.71) | 0.83(0.53,1.30) | 46(20.09) | 1.07(0.72,1.58) |
rs2241766 | Â | Â | Â | Â | Â |
TT | 278(50.09) | 91(47.64) | Reference | 99(42.23) | Reference |
TG | 238(42.88) | 87(45.55) | 1.10(0.78,1.56) | 106(46.29) | 1.25(0.90,1.72) |
GG | 39(7.03) | 13(6.81) | 1.07(0.54,2.11) | 24(10.48) | 1.71(0.97,3.01) |
TG/GG | 277(49.91) | 100(52.36) | 1.10(0.79,1.53) | 130(56.77) | 1.31(0.96.1.79) |
rs1501299 | Â | Â | Â | Â | Â |
CC | 265(47.75) | 97(50.79) | Reference | 123(53.71) | Reference |
AC | 224(40.36) | 72(37.70) | 0.86(0.60,1.24) | 88(38.43) | 0.88(0.63,1.22) |
AA | 66(11.89) | 22(11.52) | 0.93(0.54,1.60) | 18(7.86) | 0.59(0.34,1.04) |
AC/AA | 290(52.25) | 94(49.21) | 0.89(0.64,1.24) | 106(46.29) | 0.81(0.59,1.11) |
rs12733285 | Â | Â | Â | Â | Â |
CC | 477(85.95) | 175(91.62) | Reference | 211(92.14) | Reference |
CT | 78(14.05) | 16(8.38) | 0.51(0.29,0.91) | 18(7.86) | 0.51(0.30,0.88) |
TT | 0(0.00) | 0(0.00) | -- | 0(0.00) | -- |
CT/TT | 78(14.05) | 16(8.38) | 0.51(0.29,0.91) | 18(7.86) | 0.51(0.30,0.88) |
rs1342387 | Â | Â | Â | Â | Â |
GG | 210(37.84) | 99(51.83) | Reference | 114(49.78) | Reference |
AG | 263(47.39) | 69(36.13) | 0.57(0.40,0.81) | 88(38.43) | 0.62(0.45,0.87) |
AA | 82(14.77) | 23(12.04) | 0.54(0.32,0.93) | 27(11.79) | 0.66(0.40,1.09) |
AG/AA | 345(62.16) | 92(48.17) | 0.57(0.41,0.79) | 115(50.22) | 0.62(0.46,0.85) |