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Table 6 Conditional association analyses of MTNR1B genetic variants

From: Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus

Phenotype

Loci

P

Conditioned P value by

   

rs1387153

rs10830963

GDM

rs1387153

0.00008

-

0.007

 

rs10830963

0.00001

0.22

-

BMI

rs1387153

0.66

-

0.59

 

rs10830963

0.77

0.51

-

AUC_G*

rs1387153

0.00002

-

0.34

 

rs10830963

0.00006

0.11

-

HOMA_B*

rs1387153

0.0004

-

0.25

 

rs10830963

0.0007

0.07

-

HOMA_IR*

rs1387153

0.15

-

0.28

 

rs10830963

0.14

0.12

-

FPI*

rs1387153

0.58

-

0.89

 

rs10830963

0.49

0.49

-

FPG

rs1387153

0.0004

-

0.36

 

rs10830963

0.001

0.85

-

  1. Conditional P values were estimated and permutated using the software PLINK (Purcell et al.). * P values for AUC_G, HOMA_B, HOMA_IR, and FPI were calculated after normalizing their data by applying logarithms