Table 5 Multiple regression analyses of MTNR1B polymorphisms with diabetes-related phenotypes among all subjects
From: Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus
Phenotype | Loci | C/C | C/R | R/R | Pacor. | Pbcor. | Pccor. |
|---|---|---|---|---|---|---|---|
BMI | rs1387153 | 548(22.38 ± 3.65) | 888(22.37 ± 3.65) | 445(22.24 ± 3.56) | 1 | 1 | 1 |
|  | rs10830963 | 511(22.34 ± 3.60) | 904(22.33 ± 3.58) | 459(22.37 ± 3.75) | 1 | 1 | 1 |
AUC_G* | rs1387153 | 454(419.91 ± 81.85) | 743(431.31 ± 79.96) | 386(439.26 ± 74.28) | 0.0007 | 0.004 | 0.03 |
|  | rs10830963 | 419(421.23 ± 85.41) | 763(429.09 ± 78.39) | 403(439.14 ± 74.58) | 0.002 | 0.04 | 0.03 |
HOMA_B* | rs1387153 | 541(252.38 ± 190.86) | 882(239.90 ± 143.11) | 437(222.90 ± 125.81) | 0.01 | 0.29 | 0.07 |
|  | rs10830963 | 505(251.36 ± 191.00) | 897(240.78 ± 143.84) | 451(223.74 ± 128.37) | 0.03 | 0.72 | 0.04 |
HOMA_IR* | rs1387153 | 543(2.53 ± 1.63) | 882(2.59 ± 1.35) | 440(2.64 ± 1.62) | 1 | 1 | 1 |
|  | rs10830963 | 507(2.53 ± 1.47) | 897(2.57 ± 1.43) | 454(2.69 ± 1.65) | 1 | 1 | 1 |
FPI* | rs1387153 | 543(11.98 ± 6.21) | 882(12.15 ± 5.34) | 440(12.26 ± 6.56) | 1 | 1 | 1 |
|  | rs10830963 | 507(11.91 ± 5.59) | 897(12.07 ± 5.61) | 454(12.44 ± 6.64) | 1 | 1 | 1 |
FPG | rs1387153 | 454(84.30 ± 12.71) | 743(85.55 ± 12.01) | 386(86.58 ± 12.94) | 0.01 | 0.07 | 0.22 |
|  | rs10830963 | 419(84.63 ± 13.24) | 763(85.13 ± 11.62) | 403(86.71 ± 12.99) | 0.04 | 0.72 | 0.07 |