From: Estrogen and progesterone-related gene variants and colorectal cancer risk in women
Gene/Variant | N total (case/control) | MAF %1(case/control) | OR (95% CI) 2 | P trend 3 | corrected P trend 4 |
---|---|---|---|---|---|
CYP17A1 | Â | Â | Â | Â | Â |
rs10883782 | 410/834 | 15/18 | 0.78 (0.61-0.98) | 0.03 | 0.22 |
rs17724534 | 406/829 | 15/12 | 1.39 (1.08-1.78) | 0.009 | 0.07 |
CYP19A1 | Â | Â | Â | Â | Â |
rs1902584 | 410/811 | 6/5 | 1.45 (1.07-1.98) | 0.02 | 0.36 |
ESR1 | Â | Â | Â | Â | Â |
rs9340837 | 424/866 | 12/9 | 1.37 (1.05-1.79) | 0.02 | 0.73 |
CYP17A1 | Â | Â | Â | Â | Â |
rs10883782 | 47/102 | 17/13 | 1.40 (0.72-2.73) | 0.32 | 0.92 |
rs17724534 | 50/103 | 1/4 | 0.22 (0.03-1.74) | 0.12 | 0.72 |
CYP19A1 | Â | Â | Â | Â | Â |
rs1902584 | 52/108 | 6/7 | 0.79 (0.28-2.25) | 0.67 | 0.99 |
ESR1 | Â | Â | Â | Â | Â |
rs9340837 | 52/107 | 46/46 | 1.02 (0.64-1.62) | 0.95 | 0.99 |