From: Estrogen and progesterone-related gene variants and colorectal cancer risk in women
Characteristics | Cases (N = 427) | Controls (N = 871) | P value |
---|---|---|---|
Age, year | 66.6 | 66.6 | Matched |
Body mass index, kg/m2 | 27.9 | 26.9 | 0.001 |
Family history of colorectal cancer, % | 18.7 | 14.8 | 0.07 |
Colonoscopy/sigmoidoscopy exam, % | 50.0 | 57.6 | 0.01 |
History of colorectal polyps, % | 20.0 | 19.5 | 0.89 |
Hysterectomy, % | 35.4 | 34.9 | Matched |
Current smoking, % | 11.2 | 10.6 | 0.82 |
Current use of E-alone therapy, % | 19.7 | 24.0 | 0.06 |
Current use of E+P therapy, % | 15.7 | 21.2 | 0.06 |
Physical activity, MET/week | 12.4 | 14.4 | 0.009 |
Alcohol intake, drink/day | Â | Â | 0.07 |
never/past | 22.2 | 26.0 | Â |
<1 | 38.9 | 30.8 | Â |
≥1 | 38.9 | 43.2 |  |
Total calorie intake, g/day | 1437 | 1556 | 0.001 |
Tumor location | Â | Â | Â |
colon, N | 338 | N/A | Â |
rectum, N | 58 | N/A | Â |
Tumor stage | Â | Â | Â |
Localized, N | 183 | N/A | Â |
Regional, N | 152 | N/A | Â |
Distant, N | 61 | N/A | Â |