Figure 4From: Clinical and molecular characterization of a transmitted reciprocal translocation t(1;12)(p32.1;q21.3) in a family co-segregating with mental retardation, language delay, and microcephaly Reporter gene assays of the fusion sequences from derivative chromosome 12 and corresponding normal chromosome 12 sequences. (A) In the CHO cells, the construct containing the fusion sequences had luciferase activity about 1.5-fold higher than that of the construct that contained the normal sequences. (B) Similarly, in SKNSH cells, the construct containing the fusion sequences had luciferase activity about two times higher than that of the construct that contained the normal sequences.Back to article page