Table 2 Frequency of each SNP within the Sample Populations
From: Association of PGC-1alphapolymorphisms with age of onset and risk of Parkinson's disease
SNP | Alleles | PD-Cohort 1 | PD-Cohort 2 | PD-ALL | PD-EARLY-ALL | PD-LATE-ALL | All Controls | Control EARLY | Control LATE |
|---|---|---|---|---|---|---|---|---|---|
rs12374310 | GC | 71 (41.5%) | 78 (42.4%) | 149 (42.0%) | 72 (45.9%) | 62 (41.3%) | 81 (50.6%) | 35 (49.3%) | 46 (51.7%) |
| Â | CC | 70 (40.9%) | 77 (41.8%) | 147 (41.4%) | 55 (35.0%) | 68 (45.4%) | 49 (30.6%) | 21 (29.6%) | 28 (31.5%) |
| Â | GG | 30 (17.6%) | 29 (15.8%) | 59 (16.6%) | 30 (19.1%) | 20 (13.3%) | 30 (18.8%) | 15 (21.1%) | 15 (16.8%) |
rs2946385 | GT | 79 (47.0%) | 81 (45.5%) | 160 (46.2%) | 72 (47.4%) | 65 (44.5%) | 80 (50.3%) | 38 (53.5%) | 42 (47.7%) |
| Â | GG | 60 (35.7%) | 70 (39.3%) | 130 (37.6%) | 59 (38.8%) | 54 (37.0%) | 52 (32.7%) | 21 (29.6%) | 31 (35.2%) |
| Â | TT | 29 (17.3%) | 27 (15.2%) | 56 (16.2%) | 21 (13.8%) | 27 (18.5%) | 27 (17.0%) | 12 (16.9%) | 15 (17.1%) |
rs2946386 | GC | 52 (30.8%) | 77 (42.1%) | 129 (36.5%) | 55 (35.7%) | 61 (40.7%) | 49 (30.4%) | 17 (23.6%) | 32 (36.0%) |
| Â | CC | 104 (61.5%) | 93 (50.8%) | 197 (55.9%) | 88 (57.2%) | 77 (51.3%) | 98 (60.9%) | 48 (66.7%) | 50 (56.1%) |
| Â | GG | 13 (7.7%) | 13 (7.1%) | 27 (7.6%) | 11 (7.1%) | 12 (8.0%) | 14 (8.7%) | 7 (9.7%) | 7 (7.9%) |
rs2970848 | AG | 76 (45.0%) | 81 (44.3%) | 157 (44.6%) | 74 (47.7%) | 60 (40.5%) | 80 (50.0%) | 32 (44.4%) | 48 (54.5%) |
| Â | AA | 80 (47.3%) | 81 (44.3%) | 161 (45.7%) | 70 (45.2%) | 69 (46.6%) | 74 (46.3%) | 37 (51.4%) | 37 (42.0%) |
| Â | GG | 13 (7.7%) | 21 (11.4%) | 34 (9.7%) | 11 (7.1%) | 19 (12.9%) | 6 (3.7%) | 3 (4.2%) | 3 (3.5%) |
rs2970855 | AT | 80 (47.0%) | 93 (50.5%) | 173 (48.9%) | 78 (49.7%) | 72 (48.3%) | 78 (49.1%) | 32 (45.1%) | 46 (52.3%) |
| Â | TT | 69 (40.6%) | 63 (34.3%) | 132 (37.3%) | 60 (38.2%) | 53 (35.6%) | 59 (37.1%) | 31 (43.7%) | 28 (31.8%) |
| Â | AA | 21 (12.4%) | 28 (15.2%) | 49 (13.8%) | 19 (12.1%) | 24 (16.1%) | 22 (13.8%) | 8 (11.3%) | 14 (15.9%) |
rs2970865 | TC | 56 (33.2%) | 77 (41.6%) | 133 (37.6%) | 57 (36.5%) | 62 (41.3%) | 52 (32.3%) | 18 (25.0%) | 34 (38.2%) |
| Â | TT | 105 (62.1%) | 96 (51.9%) | 201 (56.8%) | 30 (57.7%) | 79 (52.7%) | 98 (60.9%) | 48 (66.7%) | 50 (56.2%) |
| Â | CC | 8 (4.7%) | 12 (6.5%) | 20 (5.6%) | 9 (5.8%) | 9 (6.0%) | 11 (6.8%) | 6 (8.3%) | 5 (5.6%) |
rs2970866 | AG | 55 (32.2%) | 75 (41.4%) | 130 (37.0%) | 54 (34.8%) | 62 (41.9%) | 50 (31.5%) | 17 (23.6%) | 33 (37.9%) |
| Â | AA | 105 (61.4%) | 94 (52.0%) | 199 (56.5%) | 90 (58.1%) | 77 (52.0%) | 97 (61.0%) | 48 (66.7%) | 49 (56.3%) |
| Â | GG | 11 (6.4%) | 12 (6.6%) | 23 (6.5%) | 11 (7.1%) | 9 (6.1%) | 12 (7.5%) | 7 (9.7%) | 5 (5.8%) |
rs2970869 | GA | 55 (33.1%) | 78 (42.2%) | 133 (37.9%) | 57 (37.0%) | 62 (41.6%) | 52 (32.1%) | 18 (24.7%) | 34 (38.2%) |
| Â | GG | 104 (62.7%) | 95 (51.3%) | 199 (56.7%) | 89 (57.8%) | 78 (52.4%) | 98 (60.5%) | 48 (65.8%) | 50 (56.2%) |
| Â | AA | 7 (4.2%) | 12 (6.5%) | 19 (5.4%) | 8 (5.2%) | 9 (6.0%) | 12 (7.4%) | 7 (9.5%) | 5 (5.6%) |
rs2970870 | TC | 83 (49.4%) | 87 (49.1%) | 170 (49.3%) | 77 (51.0%) | 73 (50.0%) | 72 (45.6%) | 26 (36.6%) | 46 (52.9%) |
| Â | TT | 54 (32.1%) | 58 (32.8%) | 112 (32.4%) | 47 (31.1%) | 47 (31.1%) | 57 (36.1%) | 29 (40.9%) | 28 (32.2%) |
| Â | CC | 31 (18.5%) | 32 (18.1%) | 63 (18.3%) | 27 (17.9%) | 27 (17.9%) | 29 (18.3%) | 16 (22.5%) | 13 (14.9%) |
rs2970873 | CT | 40 (23.4%) | 60 (33.0%) | 100 (28.3%) | 40 (25.3%) | 48 (32.6%) | 41 (25.8%) | 15 (21.1%) | 26 (29.6%) |
| Â | CC | 126 (73.7%) | 116 (63.7%) | 242 (68.6%) | 114 (72.2%) | 93 (63.3%) | 114 (71.7%) | 53 (74.7%) | 61 (69.3%) |
| Â | TT | 5 (2.9%) | 6 (3.3%) | 11 (3.1%) | 4 (2.5%) | 6 (4.1%) | 4 (2.5%) | 3 (4.2%) | 1 (1.1%) |
rs4383605 | TG | 59 (35.1%) | 73 (40.1%) | 132 (37.7%) | 55 (35.7%) | 60 (40.5%) | 59 (37.1%) | 25 (35.2%) | 34 (38.6%) |
| Â | TT | 89 (53.0%) | 97 (53.3%) | 186 (53.1%) | 84 (54.6%) | 77 (52.0%) | 83 (52.2%) | 37 (52.1%) | 46 (52.3%) |
| Â | GG | 20 (11.9%) | 12 (6.6%) | 32 (9.2%) | 15 (9.7%) | 11 (7.4%) | 17 (10.7%) | 9 (12.7%) | 8 (9.1%) |
rs6821591 | CT | 92 (53.8%) | 83 (46.3%) | 175 (50.0%) | 72 (46.8%) | 74 (50.3%) | 80 (50.3%) | 40 (56.3%) | 40 (45.4%) |
| Â | CC | 39 (22.8%) | 54 (30.2%) | 93 (26.8%) | 37 (24.0%) | 47 (32.0%) | 31 (19.5%) | 7 (9.9%) | 24 (27.3%) |
| Â | TT | 39 (22.8%) | 42 (23.5%) | 81 (23.2%) | 45 (29.2%) | 26 (17.7%) | 48 (30.2%) | 24 (33.8%) | 24 (27.3%) |
rs7665116 | CT | 39 (22.8%) | 43 (23.2%) | 82 (23.0%) | 41 (25.9%) | 31 (20.7%) | 56 (35.0%) | 26 (36.1%) | 30 (34.1%) |
| Â | TT | 128 (74.9%) | 140 (75.7%) | 268 (75.3%) | 114 (72.2%) | 119 (79.3%) | 102 (63.8%) | 45 (62.5%) | 57 (64.8%) |
| Â | CC | 4 (2.3%) | 2 (1.1%) | 6 (1.7%) | 3 (1.9%) | 0 (0.0%) | 2 (1.2%) | 1 (1.4%) | 1 (1.1%) |
rs7695542 | CT | 17 (10.1%) | 9 (4.9%) | 26 (7.4%) | 41 (26.0%) | 31 (20.7%) | 15 (9.3%) | 8 (11.1%) | 7 (7.9%) |
| Â | TT | 151 (89.9%) | 176 (95.1%) | 327 (92.6%) | 114 (72.1%) | 119 (79.3%) | 145 (90.1%) | 64 (88.9%) | 81 (91.0%) |
| Â | CC | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 3 (1.9%) | 0 (0.0%) | 1 (0.6%) | 0 (0.0%) | 1 (1.1%) |
rs8192678 | GA | 95 (53.0%) | 88 (44.3%) | 183 (48.4%) | 89 (52.7%) | 69 (43.7%) | 83 (48.0%) | 47 (58.0%) | 36 (39.1%) |
| Â | GG | 70 (39.2%) | 93 (46.7%) | 163 (43.1%) | 66 (39.0%) | 75 (47.5%) | 73 (42.2%) | 26 (32.1%) | 47 (51.1%) |
| Â | AA | 14 (7.8%) | 18 (9.0%) | 32 (8.5%) | 14 (8.3%) | 14 (8.9%) | 17 (9.8%) | 8 (9.9%) | 9 (9.8%) |
ND3 A10398G | A | 143 (79.9%) | 149 (75.6%) | 292 (77.7%) | 132 (79.0%) | 119 (75.3%) | 129 (74.6%) | 60 (74.1%) | 69 (75.0%) |
| Â | G | 36 (20.1%) | 48 (24.3%) | 84 (22.3%) | 35 (21.0%) | 39 (24.7%) | 44 (25.4%) | 21 (25.9%) | 23 (25.0%) |