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Table 3 Allelic distribution of GCKR polymorphisms and association with type 2 diabetes

From: Associations of common polymorphisms in GCKR with type 2 diabetes and related traits in a Han Chinese population: a case-control study

Alleles Non-DM (%) DM (%) Odds Ratio1a 95% CI P value Odds Ratio2b 95% CI P value
rs8179206         
A 97.0 96.6 1 (Ref.)   1 (Ref.)  
G 3.0 3.4 1.18 0.85-1.65 0.32 1.29 0.91-1.82 0.15
rs2293572         
G 85.9 85.6 1 (Ref.)   1 (Ref.)  
C 14.1 14.4 1.04 0.88-1.23 0.64 1.04 0.88-1.24 0.64
rs3817588         
A 72.1 68.0 1 (Ref.)   1 (Ref.)  
G 27.9 32.0 1.21 1.06-1.39 0.004* 1.24 1.08-1.43 0.002*
rs780094         
A 56.6 52.6 1 (Ref.)   1 (Ref.)  
G 43.4 47.4 1.19 1.05-1.34 0.005* 1.22 1.07-1.38 0.002*
  1. a Adjusted for year of birth and sex
  2. b Adjusted for year of birth, sex and BMI
  3. *Significant after Bonferroni correction (p < 0.0125 (0.05/4) was the corrected statistically significant level in association analysis between the individual SNP and type 2 diabetes)
  4. The major allele was used as a reference when comparing the risk of diabetes between alleles.