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Table 4 Logistic regression model for preeclampsia, including presence of the rs2549782 minor allele in African American fetuses.

From: Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study

Term

Estimate (S.E.)

P-value

Odds Ratio (95% C.I.)

Fetal rs2549782

0.425 (0.169)

0.012

1.529 (1.099, 2.128)

Maternal BMI

0.021 (0.014)

0.140

1.021 (0.993, 1.049)

Previous live births

- 0.168 (0.065)

0.010

0.845 (0.744, 0.960)

Fetal Sex (% female)

0.355 (0.228)

0.120

1.426 (0.912, 2.231)

Intercept

-1.810 (0.492)

< 0.001

-

  1. S.E., standard error; C.I., confidence interval; BMI, body mass index. The minor allele (G) of rs2549782 significantly increases the risk for preeclampsia in African American fetal samples; after correcting for risk factors identified to modulate risk in this population.
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BMC Medical Genetics

ISSN: 1471-2350

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