Skip to main content
Figure 3 | BMC Medical Genetics

Figure 3

From: SNPs and real-time quantitative PCR method for constitutional allelic copy number determination, the VPREB1 marker case

Figure 3

Representation of Chromosome 22 with enlargement of the 22q11.2 region and qPCR markers locations. qPCR markers localization was shown with respect to the two most classical 3 Mb and 1.5 Mb microdeletions and two different examples of atypical deletions. PRODH, TUPLE1 and COMT markers recognized 3 Mb and 1,5 Mb microdeletions; D22S936 marker allowed to distinguish between 3 Mb or 1.5 Mb microdeletions; D22S181 and VPREB1, both localized outside the critical deletion region, allowed the detection of respectively proximal and distal atypical microalterations.

Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us