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Table 5 Frequency of CD16A alleles and genotypes among MD patients and healthy controls.

From: Polymorphisms of CD16A and CD32 Fcγ receptors and circulating immune complexes in Ménière's disease: a case-control study

Southeast

MD N = 156 (%)

Controls N = 626 (%)

OR (95% CI)

Fisher's exact p values

Corrected p

AA

70 (44.9)

221 (35.3)

1.49 (1.05-2.12)

0.018

0.054

AC

60 (38.5)

314 (50.2)

0.62 (0.43-0.89)

0.006

0.018

CC

26 (16.7)

91 (14.5)

1.17 (0.73-1.89)

0.29

NS

Allele

2n = 312 (%)

2n = 1252 (%)

1.17 (0.91-1.52)

0.13

NS

A

200 (64.1)

756 (60.4)

   

C

112 (35.9)

496 (39.6)

   

Northwest

MD N = 110 (%)

Controls N = 141 (%)

OR (95% CI)

Fisher's exact p values

Corrected p

AA

46 (41.8)

73 (51.8)

0.67 (0.40-1.11)

0.07

NS

AC

50 (45.5)

54 (38.3)

1.34 (0.80-2.23)

0.15

NS

CC

14 (12.7)

14 (9.9)

1.32 (0.60-2.91)

0.31

NS

Allele

2n = 220 (%)

2n = 282 (%)

0.75 (0.51-1.09)

0.08

NS

A

142 (64.5)

200 (70.9)

   

C

78 (35.5)

82 (29.1)

   
  1. No additive effect was observed in homozygous subjects with Cochran-Armitage trend test in the southeast (p = 0.23) and the northwest group (p = 0.14).