|  |  | Fetal haplotypes | Maternal haplotypes | Combined | ||||
---|---|---|---|---|---|---|---|---|---|
markers | haplotype | freq | RR | 95% CI | p | RR | 95% CI | p | Overall p |
rs6760780-rs3923384-rs6434317 | T-A-C | 0.830 | 1.00 | - | - | 1.00 | - | - | 0.013 |
 | T-A-A | 0.091 | 0.65 | 0.41, 1.05 | 0.077 | 1.20 | 0.77, 1.86 | 0.419 |  |
 | A-G-A | 0.041 | 1.82 | 1.06, 3.08 | 0.030 | 0.78 | 0.44, 1.41 | 0.413 |  |
 | A-A-A | 0.037 | 0.33 | 0.14, 0.81 | 0.014 | 1.48 | 0.76, 2.88 | 0.244 |  |
rs3923384-rs6434317-rs6434322 | A-C-G | 0.828 | 1.00 | - | - | 1.00 | - | - | 0.006 |
 | A-A-G | 0.129 | 0.54 | 0.36, 0.82 | 0.004 | 1.26 | 0.87, 1.84 | 0.241 |  |
 | G-A-A | 0.042 | 1.81 | 1.06, 3.10 | 0.029 | 0.78 | 0.43, 1.39 | 0.393 |  |
rs6434317-rs6434322-rs10165260 | C-G-A | 0.829 | 1.00 | - | - | 1.00 | - | - | 0.006 |
 | A-G-A | 0.129 | 0.55 | 0.36, 0.83 | 0.006 | 1.27 | 0.88, 1.84 | 0.210 |  |
 | A-A-G | 0.042 | 1.81 | 1.06, 3.10 | 0.026 | 0.77 | 0.43, 1.40 | 0.385 |  |
rs6434322-rs10165260-rs7420331 | G-A-A | 0.829 | 1.00 | - | - | 1.00 | - | - | 0.006 |
 | G-A-G | 0.129 | 0.54 | 0.36, 0.82 | 0.004 | 1.26 | 0.87, 1.83 | 0.232 |  |
 | A-G-A | 0.042 | 1.80 | 1.06, 3.11 | 0.026 | 0.78 | 0.43, 1.39 | 0.392 |  |
rs10165260-rs7420331-rs13024858 | A-A-A | 0.792 | 1.00 | - | - | 1.00 | - | - | 0.041 |
 | A-G-A | 0.109 | 0.58 | 0.37, 0.91 | 0.018 | 1.33 | 0.90, 1.97 | 0.159 |  |
 | A-A-C | 0.035 | 1.46 | 0.78, 2.76 | 0.242 | 0.70 | 0.35, 1.44 | 0.329 |  |
 | G-A-A | 0.022 | 2.23 | 1.12, 4.57 | 0.023 | 0.63 | 0.28, 1.40 | 0.262 |  |
 | A-G-C | 0.020 | 0.38 | 0.10, 1.55 | 0.175 | 0.72 | 0.23, 2.29 | 0.582 |  |
 | G-A-C | 0.019 | 1.44 | 0.65, 3.20 | 0.362 | 0.95 | 0.42, 2.23 | 0.901 |  |
rs7420331-rs13024858-rs6752781 | A-A-A | 0.817 | 1.00 | - | - | 1.00 | - | - | 0.043 |
 | G-A-A | 0.109 | 0.55 | 0.35, 0.86 | 0.009 | 1.37 | 0.92, 2.05 | 0.116 |  |
 | A-C-G | 0.053 | 1.41 | 0.86, 2.38 | 0.187 | 0.83 | 0.48, 1.42 | 0.516 |  |
 | G-C-G | 0.020 | 0.47 | 0.13, 1.81 | 0.277 | 0.70 | 0.22, 2.22 | 0.542 |  |